The following article says that more stringent criteria are necessary to diagnose primary hyperaldosternism. What about just for differentiation between primary and secondary hyperaldosteronism? Would renin levels be sufficient there? :notsure: http://emedicine.medscape.com/article/117280-diagnosis
Yes the answer is:
- primary hyperaldosteronism (Conn's syndrome) = low renin
Caused by adrenal adenoma mostly, do CT for abdomen.
- secondary hyperaldosteronism = high renin
More common than primary, and related to hypertension (renal artery stenosis) and edematous disorders (CHF, nephrotic, cirrhosis).
difference between primary and secondary hyperaldosteronism
primary is due to adenoma in zona glomerulosa lab findings hypernatremia hypoklemiametabolic alkalosisand associated hypertensionplasma renin is dec in secondary hyperaldosteronism plasma renin activity increase dec renal bd flow activates the renin angiotensin aldosterone system it is compensatory reaction to dec cardic out put
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