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Old 03-30-2011
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Kidney Can Nephrotic Syndrome be infectious?

Does anyone know if it is possible to transmit nephrotic syndrome (minimal change disease) through blood transfusion of one patient to another? When both of the lab reports are showing the same levels of BUN and Creatinine.
The possibly infected patient also has a high WBC count?
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Old 03-30-2011
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As far as I know that some studies have shown that there could some factors in the blood that may play role in the causation of proteinuria, but these factors have never been identified and proved to be the sole etiology of minimal change disease.

There has been reports that Nephrotic Syndrome might be transmitted transplacentally to newborns but I searched the literature and I did not find a single report of such a transmission via blood transfusion.

Where did you get that info? was it a USMLE question?
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Old 03-30-2011
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No, a friend of mine was stuck with a hypodermic needle of a combative patient and then developed this disease shortly after. Iíve heard of some of the risk factors:
  • Medical conditions that can damage your kidneys. Certain diseases and conditions increase your risk of developing nephrotic syndrome, such as diabetes, lupus, amyloidosis, minimal change disease and other kidney diseases.
  • Certain medications. Examples of medications that can cause nephrotic syndrome include nonsteroidal anti-inflammatory drugs and drugs used to fight infections.
  • Certain infections. Examples of infections that increase the risk of nephrotic syndrome include HIV, hepatitis B, hepatitis C and malaria.
  • Drugs - Nonsteroidal anti-inflammatory drugs (NSAIDs), rifampin, interferon, ampicillin/penicillin, trimethadione, mercury-containing cosmetic skin cream
  • Toxins - Mercury, lithium, bee stings, fire coral exposure
  • Infection - Infectious mononucleosis, HIV, immunization
  • Tumor - Hodgkin lymphoma (most commonly), carcinoma, other lymphoproliferative diseases
  • Posthematopoietic stem cell transplant
The patient had a UTI, Decubitis Ulcers, Edema, Renal Failure, Convulsions, Anemia, Alzheimerís, and Hypertension
Hepatitis result were unknown.

Meds: Cipro, Namenda, Valpro, Protonix, Zocor, Iron, Zantac, Tylenol, Xalatan, and Ferrus Sulfate
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Immunology-, Nephrology-

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