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some facts about lithium

7K views 4 replies 5 participants last post by  bebix 
#1 ·
Hey guys just trying to put up some effects of lithium as far as i studied

LITHIUM

1) lithium is used as mood stabilizer

2) lithium causes hypercalcemia ----->shifts Ca/PTH curve to right

3) lithium causes hypothyroidism

i would appreciate if someone will add other HY points:cool:
 
#5 ·
Lithium

"LMNOPQST"

L = Lithium
M = Movement (tremor)
N = Nephrogenic DI (V2 receptor, which is Gs) / Narrow therapeutic index
O = hipOthyroidism (TSH act in a Gs receptor)
P = Pregnancy problems (Ebstein)
Q = inhibits Gq due to the fact that decrease IP3 (dec. IP2 & DAG)
S = inhibits Gs due to the fact that decrease AMPc / Seizures
T = Torsades de pointes
 
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