Important causes of Amenorrhea for step 1 - USMLE Forums
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USMLE Step 1 Bits & Pieces High yield short focused points, monographs, charts, illustrations, tables, and other stuff related to the USMLE Step 1 Exam.


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Old 10-19-2011
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List Important causes of Amenorrhea for step 1

Important causes of amenorrhea for step 1
  • Complete androgen insensitivity syndrome
  • Turner syndrome
  • Anorexia nervosa
  • Prolactinoma
  • Polycystic ovarian syndrome
  • Sheehan syndrome

Causes of amenorrhea that may not be so important for step 1
  • Müllerian agenesis
  • cervical stenosis
  • vaginal septum
  • imperforate hymen
  • asherman's syndrome
  • ovarian insufficiency, including menopause
  • drugs causing hyperprolactinemia
  • hypothyroidism
  • pregnancy
  • Kallman's syndrome
  • pituitary causes, other than sheehan (such as radiation)
  • sarcoidosis
  • autoimmune (such as oophoritis)
  • infectious (such as TB)

I will take suggestions and edit this post as necessary.
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Old 10-19-2011
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how abt amenorrhea in female athletes!
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Quote:
Originally Posted by shyangel18 View Post
how abt amenorrhea in female athletes!
Agree!
Exercise-induced amenorrhea is most commonly seen in women whose exercise regimen is associated with significant loss of fat, such as ballet, gymnastics, and long-distance running.

for some reason I thought I would be able to edit the original post, and update the list, but I can't.
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Old 10-20-2011
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can u xplain the pathophysiology behind it. and what are the complications?? i saw a similar question in one of the NBMEz asking abt the most common outcome of female athlete..
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Old 10-20-2011
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Originally Posted by shyangel18 View Post
can u xplain the pathophysiology behind it. and what are the complications?? i saw a similar question in one of the NBMEz asking abt the most common outcome of female athlete..
The "female athlete triad" includes amenorrhea, eating disorder, and osteoporosis. Elite athletes can have amenorrhea too, even without an eating disorder, this is associated to very low body fat. As for the mechanism, it is hypothalamic, with a decrease in frequency and amplitude of GnRH pulses.

If you ask why would an athlete have hypothalamic GnRH suppression, then the answer is not well known (likely outside USMLE territory). According to Greenspan’s Basic & Clinical Endocrinology it appears that leptin (which is produced by adipocytes and proportional to body fat) stimulates both the hypothalamus and the gonadotropes, so no fat = no leptin = no GnRH = no menses.
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oh well thanx a lot!!!
i chose the right answer they asked for complication. n i chose osteoporosis! but stupid offline NBMEz hav so many worng answers!! they r so misleading!
thanx anyways
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