Infectious Dose (inoculum) of Important bugs! - USMLE Forums
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Old 12-13-2011
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Smile Infectious Dose (inoculum) of Important bugs!

Here is the infective doses of various pathogenic organisms necessary to start the disease......

E. histolytica - as few as 1 organism
Giardia lambia - as few as 1 organism
Shigella - 10-200
C. jejuni - around 500
C. perfringens - around 500
Vibrio cholerae - 10,00,000(01 & 0139 serotypes)
V. parahemolyticus - 10-5 to 10-7 organisms
ETEC - 10-8 TO 10-10 organisms

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Old 12-13-2011
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Default Is that needed ?

Is it important to know the load needed to start a disease ?
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Old 12-13-2011
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Quote:
Originally Posted by dr-ahmed View Post
Is it important to know the load needed to start a disease ?
As far as I've seen in UW (I haven't read all microbiology questions), there was a question about the infection dose between shigella and salmonella, so I guess the answer is.... YES.

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Old 12-13-2011
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Francisella: ~10 organisms (most labs will not culture )
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Old 05-15-2012
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Salmonella ---> 10^7 microorganism to get an infection
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Old 05-18-2012
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But in case of Salmonella typhi species only 10^5 organisms
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Old 06-25-2012
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yes sir that fact is listed in fa!
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Old 06-28-2012
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Also remember what bugs have a higher chance of developing a disease when taking a ppi (proton pump inhibitor) ex. V. cholera.
Acidity in stomach is decreased so a large dose of organism is not required.
Basically remember whatever can be degradedby stomach acid can cause disease when using ppi. This is a question in u worl
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