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Old 02-10-2012
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Thumbs Up Anti-Helminths Drug of Choice

Source: My revision from Katzung Pharmacology


NEMATODES
a. Ascaris-“PAM” Pyrantel palmoate, Albendazole, Mebendazole
b. Hookworm- -“PAM” Pyrantel palmoate, Albendazole, Mebendazole
c. Trichuris- “AM” Albendazole, Mebendazole
d. Strongyloides- Ivermectin
e. Enterobius- “PM” Pyrantel palmoate, Mebendazole
f. Trichinella- Mebendazole
g. Cutaneous larva migrans- “AI” Albendazole, Ivermectin
h. Wuchereria & Brugia- DEC
i. Onchocerca volvulus- Ivermectin

TREMATODE
a. Schistosoma haematobium- Praziquantel
b. Schistosoma mansoni- Praziquantel
c. Schistosoma japonicum- Praziquantel
d. Paragonimus westermani- Praziquantel
e. Fasciola hepatica- Bithionol or Triclalbendazole
f. Fasciolopsis buski- Praziquantel or Niclosamide

CESTODE
a. Taenia saginata- Praziquantel or Niclosamide
b. Taenia solium- Praziquantel or Niclosamide
c. Cysticercosis- Albendazole
d. Diphylobothrium latum- Praziquantel or Niclosamide
e. Echinococcus granulosus: Albendazole
f. Loa loa: DEC
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Old 02-10-2012
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Interesting what DEC is and how loa loa is different from regular prazi-pira-mebendazole cocktail...
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Quote:
Originally Posted by DocSikorski View Post
Interesting what DEC is and how loa loa is different from regular prazi-pira-mebendazole cocktail...
DEC= Diethylcarbamazine
"DEC is drug of choice for loa loa (eyeworm) and an alternative for elephantiasis" (Katzung & Trevor's Pharmacology 8th edition Chapter 54, page 443); Sorry I don't know how it is different from the regular prazi-pira-mebendazole. Any further inputs would be nice so as we could all learn from this
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