Hypopituitarism, why hypoglycemia? - USMLE Forums
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Old 08-15-2009
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Default Hypopituitarism, why hypoglycemia?

The anterior pituitary is "diabetogenic"

Three hormones play role
1- Growth Hormone, decreases tissue (liver and muscle) sensitivity to insulin and that's why acromegalic patients may have DM.
2- ACTH, as it will release cortisol which in turn is also anti-insulin and that's why cushings have DM.
3- TSH, as it will release thyroid hormone which is thought to increase glucose absorption from the gut that's why postprandial glucosuria in Grave's disease.

So then a damage to the anterior pituitary should certainly result in hypoglycemia
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The above post was thanked by:
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