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Old 08-28-2009
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Urine Sample Diuretics Rules & Exceptions

  • They all block Na reabsorption along the tubule
  • They all cause hypokalemia EXCEPT K sparing diuretics
  • Thiazides cause hypertriglyceridemia EXCEPT Indapamide
  • K sparing diuretics are antiandogenic EXCEPT Eplerenone
  • Loop diuretics cause sulfa allergy EXCEPT Ethacrynic acid
  • Hyperglycemia mostly caused by Thiazides
  • Only Thiazides cause hypercalcemia, all others cause hypocalcemia
  • Acidosis is seen with carbonic anhydrase inhibitors and K sparing diuretics
  • Alkalosis is seen in loop and Thiazides diuretics
  • Hyperchloremia is seen only in carbonic anhydrase inhibitors
  • Caffeine works on vasodilating the glomerular vessels unlike all other diuretics which work on blocking Na reabsorption
  • Carbonic anhydrase inhibitors paradoxically cause renal stones because they result in basic urine (bicarbonateuria)

Last edited by rasheed; 06-25-2010 at 08:44 AM.
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Old 03-09-2010
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Very useful
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Pharmacology-, Renal-

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