Good points about Multiple Myeloma - USMLE Forums
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USMLE Step 1 Bits & Pieces High yield short focused points, monographs, charts, illustrations, tables, and other stuff related to the USMLE Step 1 Exam.


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Old 07-31-2012
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Smile Good points about Multiple Myeloma

  • Bone punched out lesion...> due to osteoclasts activating factor, and osteoblasts differentiation inhibitor.
  • When light chains get converted into amyloid, they cause nephrotic syndrome.
  • Proteinaceous tubular casts in urine (light chains), tubular basement membrane calcinosis, and acute renal failure.
  • Normocytic anemia, rouleaux formation, quantitative platelets defect.
  • Most common cause of death is infection (St.pneumonia, and H.influenza)
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