Disulfiram Like Reaction (Drugs with Disulfiram like effects) - USMLE Forums
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Old 02-28-2011
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Drug Disulfiram Like Reaction (Drugs with Disulfiram like effects)

Drugs that cause Disulfiram like reaction are commonly tested in USMLE and they are high yield and must be known.

This is a list of drugs which can produce DISULFIRAM like reaction when taken with Alcohol:

--Antbiotics such as METRONIDAZOLE
--Cephalosporins such as CEFOPERAZONE, CEFAMANDOLE, and CEFOTETAN (it's thought that Methylthiotetrazole side chain in these cephalosporins is responsible for aldehyde dehydrogenase block (disulfiram like effects) and also for blocking vitamin K epoxide reductase therefore they also cause hypoprothrombinemia).
--First generation sulphonylureas such as CHLORPROPAMIDE and TOLBUTAMIDE
--Antifungal drug GRISEOFULVIN
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Old 09-08-2015
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Default Thanks for the compilation...

And for the sake of completion:

Procarbazine, a chemotherapeutic agent used in Hodgkin's.
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