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USMLE Step 1 Classic Clues Classic clues seen in clinical case scenarios in USMLE Step 1 questions.


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  #1  
Old 08-21-2009
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ObGyn Postmenopausal Bleeding

If the case tells you bleeding after menopause then it's Endometrial Carcinoma until proven otherwise
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  #2  
Old 08-22-2009
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Why women have endometrial cancer in the menopause?
I believe that the have less estrogen!
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Old 08-22-2009
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Quote:
Why women have endometrial cancer in the menopause?
I believe that the have less estrogen!
In menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.
The source of postmenopausal estrogen is the adrenal zona reticularis where DHEA is produced and then aromatized in ovarian stroma and fatty tissues to Estrone.
It's the effect of unopposed estrone (as no more progesterone from corpus letuem) that causes endometrial hyperplasia which is a precursor of endometrial carcinoma, the most common female genital cancer in the aging US population and the second killer after ovarian cancer.
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Old 04-23-2012
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Quote:
Originally Posted by StepTaker View Post
In menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.
The source of postmenopausal estrogen is the adrenal zona reticularis where DHEA is produced and then aromatized in ovarian stroma and fatty tissues to Estrone.
It's the effect of unopposed estrone (as no more progesterone from corpus letuem) that causes endometrial hyperplasia which is a precursor of endometrial carcinoma, the most common female genital cancer in the aging US population and the second killer after ovarian cancer.
or it can be due to hormone replacement therapy and more estrogen in dat....:-)
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Old 04-01-2015
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the patient will be mostly an obese woman ..obesity is a high risk factor. adrenal androgens will b converted to estrogens.. and etiology of endometrial cancers is estrogen..
mc gynaecological cancer in post menopausal age is endometrial
mc cause of death by gynaecological cancer is ovarian cancer
mc overall cause of death is heart disease
and most common cancer is lung cancer
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Old 10-16-2015
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Quote:
Originally Posted by beverly View Post
Why women have endometrial cancer in the menopause?
I believe that the have less estrogen!
TO much cycles of menstruation. like early menarche or late menopause!!
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  #7  
Old 02-28-2016
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Quote:
Originally Posted by StepTaker View Post
In menopause, you still have some estrogen although it's reduced compared to its premenopausal levels.
The source of postmenopausal estrogen is the adrenal zona reticularis where DHEA is produced and then aromatized in ovarian stroma and fatty tissues to Estrone.
It's the effect of unopposed estrone (as no more progesterone from corpus letuem) that causes endometrial hyperplasia which is a precursor of endometrial carcinoma, the most common female genital cancer in the aging US population and the second killer after ovarian cancer.

thanks for explaining
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Old 03-02-2016
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postmenopausal estrogen is produced mainly by ovaries and that estrogen leads to endometrial carcinoma in women
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  #9  
Old 07-21-2016
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Default THanks

This is good to know
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Old 08-08-2016
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Default thank you

Thank you so much
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Old 09-01-2016
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thank you! its been very helpful!!
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Old 09-12-2016
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good wxplination
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Old 10-02-2016
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it related to Early menarche or Late menopause. Post menopausal estrogen Estrogen cause endometrial carcinoma.
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Posted By For Type Date
Post Menopausal Bleeding on RightHealth This thread Refback 12-10-2009 03:39 AM
Postmenopausal Bleeding on RightHealth This thread Refback 11-04-2009 06:07 PM

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