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USMLE Step 1 Classic Clues Classic clues seen in clinical case scenarios in USMLE Step 1 questions.


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  #1  
Old 09-30-2009
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Neuro Alzheimer disease sudden death

If the question stem describes an elderly patient with history of Alzheimer disease who suddenly dies or suffered stroke then think
Cerebral Amyloid Angiopathy

This is the same amyloid deposited in neurones in Alzheimer patients gets deposited in the blood vessels media and render them friable.

So there will be a risk of sudden severe hemorrhagic stroke that may kill the patient on the spot.

The other name for cerebral amyloid angiopathy is cerebral congophilic angiopathy, the latter name stems from the fact that amyloid stained with congo red stain.
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Old 10-04-2009
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But we should be very careful as the question might be simply asking about berry's aneurysm
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Old 06-05-2010
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and the amylois is APP amyloid precursor protien
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