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Old 07-27-2014
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Default Failure to bind LDL to its receptor

Failure to bind LDL to its receptor results in uncontrolled synthesis of cholesterol. This occurs because synthesis of which of the following enzymes is not repressed?

(A) Acyl CoA cholesterol acyltransferase
(B) 3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase
(C) Lecithin-cholesterol acyltransferase
(D) Lipoprotein lipase
(E) Lysosomal protease
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Old 07-27-2014
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HMG-CoA reductase (recall: statins inhibit HMG-CoA reduc. action, thereby up regulating LDL receptor expression)
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