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  #1  
Old 06-06-2011
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Lungs Sputum Cytology Question

A 65 y/o African-American woman with a 40 pack/year history of smoking has been having persistent cough for about 2 months and shortness of breath for the past three weeks.
The following is her sputum citology (Papapinocolaou stain):

Sputum Cytology Question-lung2.jpg
click image to enlarge

Which of the following is the most likely diagnosis?


a) Adenocarcinoma
b) Squamous cell carcinoma
c) Large cell carcinoma
d) Small cell lung carcinoma
e) Sarcoidosis
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  #2  
Old 06-06-2011
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Default answer -- E

I think its sarcoidosis ....according to sputum cytology its seems to b noncaseating granuloma ...
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Old 06-06-2011
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I remember Goljan saying...pap smear in the lung with something red in it is Squamous cell carcinoma...so, my answer is b.
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Old 06-06-2011
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Oat cells??? Small cell???
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the answer is b
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Quote:
Originally Posted by bebix View Post
A 65 y/o African-American woman with a 40 pack/year history of smoking has been having persistent cough for about 2 months and shortness of breath for the past three weeks.
The following is her sputum citology (Papapinocolaou stain):

Attachment 1445

Which of the following is the most likely diagnosis?


a) Adenocarcinoma
b) Squamous cell carcinoma
c) Large cell carcinoma
d) Small cell lung carcinoma
e) Sarcoidosis
I will go with E..sarcoidosis.
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Old 06-06-2011
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i will go with B..!!
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Old 06-06-2011
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this must be b)
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I should go with B, but i dont know why i keep telling my self i see "neurosecretory granules on this smear" which point me to Small ceel Answer D, if i have to go, i choose D and wait for the consequence .... hahaha

So Answer is D for me.
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Old 06-06-2011
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Pap smear of sputum showing Keratin (red) stained , Squamous cell CA?
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is it b??
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squamous cell ca.
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Default Ans.

I choose b., though i'm not sure about seeing the keratin pearls clearly, but the smoking association and the way cells are closed together makes me think of squamous cell carcinoma.
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The answer is b: squamous cell carcinoma. I looked at google images and it showed me the exact same picture for pap stain of squamous cell carcinoma.
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PAP smear for sputum cytology with smoking history.with pink satining cells .i wud put my money in sq cell ca..
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Correct Answer correct answer

Quote:
Originally Posted by heman466s View Post
PAP smear for sputum cytology with smoking history.with pink satining cells .i wud put my money in sq cell ca..
YES.
This cytology is from a patient with b) Squamous cell carcinoma.
Remember: No one expects us to be pathologists ... if you see a PAP smear with reddish/pink/orange "stuff" in it...think squamous.

This is from:
Dail and Hammarís Pulmonary Pathology Volume II: Neoplastic Lung Disease, chapter 45.

Also, you can find another picture in Goljan RRPathology p. 309-A
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  #17  
Old 06-07-2011
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i am really bad at cytology.. i would go wid B as it is the most common cancer in smokers....
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