43 y/o women had a history of several months of progressive loss of appetite, early satiety and weight loss. She also had an endoscopic image informed as "walls of the stomach appeared thickened, and the stomach distended poorly". She died and the pathologist found this in her stomach:
click image to enlarge
A) This lesion is associated with H. pylori
B) This lesion is more common in postmenopausal women
C) Peritoneal spread can present with an enlarged ovary
D) If detected early, this lesion has a good prognosis
E) This patient must have had pernicious anemia
I think C. I think it is a Linitis Plastica and it is very aggressive and can metastasized to other parts. But this is kinna tricky question because Linitis Plastica can be seen from metastasis of Breast cancer in a post menopausa woman. So in this case, B can be a possible hard choice. But I would stick with C.
- aka "leather bottle"
-women:men ratio = 60%/40%
-Risk of Krukenberg tumor (15%).
-The median survival time: 8 months for those with M1 cancer.
-10% of the patients had a family history of gastric carcinoma (familial forms of gastric linitis and breast cancer-associated forms have been reported)
- Age of onset is below 40y/o
- not associated with H.pylori
- Singet-ring cells present
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