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  #1  
Old 06-13-2011
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Drug A 30 y/o woman with depressive symptoms

A 30 y/o woman has a history of depressive symptoms and body aches. Physical exam and blood tests are normal. Which of the following drugs might be useful in this patient?

A) Fluoxetine
B) Sertraline
C) Phenelzine
D) Duloxetine
E) Mirtazapine
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Any one of them?
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is it sertraline?
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Quote:
Originally Posted by Tig2575 View Post
Any one of them?
haha...I also had this question wrong... one of the drugs is "the one" we should use in this particular case
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Fluoxetine is the prototype SSRI
Sertraline is an SSRI with a shorter half life and much quicker onset of action
Phenelzine is an MAOi that should only be used first line for atypical depression
Duloxetine is an SSNRI that also treats diabetic peripheral neuropathy
Mirtazapine is a central alpha-2 blocker that causes sedation and increased appetite
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is it c: sertaline?
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Quote:
Originally Posted by Tig2575 View Post
Fluoxetine is the prototype SSRI
Sertraline is an SSRI with a shorter half life and much quicker onset of action
Phenelzine is an MAOi that should only be used first line for atypical depression
Duloxetine is an SSNRI that also treats diabetic peripheral neuropathy
Mirtazapine is a central alpha-2 blocker that causes sedation and increased appetite
FA?

this qs is from Lippincottīs pharm
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Just what I know of them off the top of my head.
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Old 06-13-2011
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Quote:
Originally Posted by bebix View Post
A 30 y/o woman has a history of depressive symptoms and body aches. Physical exam and blood tests are normal. Which of the following drugs might be useful in this patient?

A) Fluoxetine
B) Sertraline
C) Phenelzine
D) Duloxetine
E) Mirtazapine
I think it si Phenelzine..
Because MAO inhibitors are used in atypical depression and hypochondriasis..

Last edited by struggle; 06-13-2011 at 08:31 AM. Reason: wrote typical instead of atypical..
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Quote:
Originally Posted by bebix View Post
A 30 y/o woman has a history of depressive symptoms and body aches. Physical exam and blood tests are normal. Which of the following drugs might be useful in this patient?

A) Fluoxetine
B) Sertraline
C) Phenelzine
D) Duloxetine
E) Mirtazapine
the correct answer is D) Duloxetine

According to Lippincottīs pharm, "Duloxetine is an SNRI that can be used for depression accompanied by neuropathic pain. MAOs and SSRIs have little activity against neuropathic pain."
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  #11  
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OH i thought the body aches are due to hypochondriasis..
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I must demure: the question stem offered no possible way to discern the nature of the patient's pain - "body aches" isn't sufficient evidence to make a diagnosis of neuropathic pain, it could easily be caused by a number of other potential conditions (like fibromyalgia, which is associated with depression and is partially treated with tricyclics or SSRIs). It's never a good idea on real USMLE questions to "read into" the question and assume something that can't be deduced with the information present.
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Quote:
Originally Posted by Tig2575 View Post
I must demure: the question stem offered no possible way to discern the nature of the patient's pain - "body aches" isn't sufficient evidence to make a diagnosis of neuropathic pain, it could easily be caused by a number of other potential conditions (like fibromyalgia, which is associated with depression and is partially treated with tricyclics or SSRIs). It's never a good idea on real USMLE questions to "read into" the question and assume something that can't be deduced with the information present.
Iīm with you on this one...thatīs way I wrote "According to Lippincottīs pharm" (p.158)...

Last edited by bebix; 06-13-2011 at 11:30 AM. Reason: added info
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My mistake! I thought you had taken the info from the book and created your own question from it. I'm sorry for critiquing you unfairly
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