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  #1  
Old 06-19-2011
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Drug Mechanism of action of these drugs...

A- Bendroflumethiazide
B- Inhaled insulin
C- Glucagon
D- Insulin glargine
E- Acarbose
F- Gliclazide
G- Pioglitazone
H- Orlistat
I- Insulin lispro
J- Metformin


Link each of 1 to 5 below with the most appropriate item from A to J:

1- Lactic acidosis
2- Rapid hypoglycaemic effect
3- Useful in treatment of hypoglycaemia in a comatose patient
4- Action on a nuclear receptor
5- Depolarizes pancreatic islet beta cells
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Old 06-19-2011
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[QUOTE=bebix;47773]A- Bendroflumethiazide
B- Inhaled insulin
C- Glucagon
D- Insulin glargine
E- Acarbose
F- Gliclazide
G- Pioglitazone
H- Orlistat
I- Insulin lispro
J- Metformin


[B]Link each of 1 to 5 below with the most appropriate item from A to J:

1- Lactic acidosis ...METFORMIN
2- Rapid hypoglycaemic effect ...INSULIN LISPRO
3- Useful in treatment of hypoglycaemia in a comatose patient ....IV GLUCAGON
4- Action on a nuclear receptor ...PIOGLITAZONE (thru PPAR)
5- Depolarizes pancreatic islet beta cells....GLICLAZIDE
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  #3  
Old 06-19-2011
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I never heard of bendroflumethiazide..
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Old 06-19-2011
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Quote:
Originally Posted by struggle View Post
I never heard of bendroflumethiazide..
Never heard of it, but I would guess its a thiazide diuretic
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  #5  
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yeah agree with struggle.. and it looks like thiazide to me too..
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Old 06-20-2011
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Correct Answer correct answer

1-J. Metformin is the drug of choice in overweight diabetic patients in whom diet is inadequate. It should be avoided in patients with renal impairment due to the risk of lactic acidosis.

2-I. Insulin lispro has a more rapid and shorter duration of hypoglycaemic action than natural insulin.

3-C. Glucagon, via stimulation of adenyl cyclase, stimulates glycogen breakdown and gluconeogenesis.

4-G. Pioglitazone binds to PPAR γ, a nuclear receptor.

5-F. Gliclazide, a sulphonylurea, depolarizes pancreatic islet beta cells,thereby stimulating insulin secretion.
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