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Old 06-20-2011
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Drug How propranalol helps in Migraine headache

guys i dont understand
How does propranolol act in migraine headache?
plz help
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Old 06-20-2011
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Quote:
Originally Posted by drciri View Post
Beta-blockers have been used for many years to prevent migraine headaches.

It is not known how beta-blockers prevent migraine headaches. It may be by decreasing prostaglandin production, though it also may be through their effect on serotonin or a direct effect on arteries...

(i copy pasted dis )
not sure but..
Very important point is, they're used prophylactically, never as treatment.
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Old 06-21-2011
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cuz migrane is due to vasodilation and B blocker stops vasodilation (recall b2 receptors cause vasodilation) and B blocker inh that action!
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The above post was thanked by:
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Nervous-System-, Pharmacology-, Physiology-

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