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  #1  
Old 06-26-2011
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Question endocrinology question

A large dose of insulin is administered intravenously to a patient. Which of the following sets of hormonal changes is most likely to occur in the plasma in response to the insulin injection?

table.bmp

A) A
B) B
C) C
D) D
E) E
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  #2  
Old 06-26-2011
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C

all hormones should be boosted up...
if cortisol is also in list then it should also be increased
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Old 06-26-2011
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C)

Keep in mind that this is IV administration, if i was endogenous, insulin release, glucagon would not be up, somatostatin would be up so would GH and but Epinephrine would be invariable (A).

Stress Hormones:

Cortisol, Epinephrine, Glucagon, and Growth Hormone are released

Antagonist Activity:

Insulin, Somatostatin.
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we have discussed this question with CONRAD FISCHER he told us same option as i told....
he spent five mints on it
and i m sticking with him and so option C
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Old 06-26-2011
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Actually i didnt get that how all stress hormones will be increased..
they are supposed to be decreased..because the alpha cells inhibit beta cell secretion and viceversa..
Sorry if someone can explain it in a bit detail..
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Old 06-26-2011
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Quote:
Originally Posted by struggle View Post
Actually i didnt get that how all stress hormones will be increased..
they are supposed to be decreased..because the alpha cells inhibit beta cell secretion and viceversa..
Sorry if someone can explain it in a bit detail..
i too thought it would decrease and the answer E????
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Old 06-26-2011
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Default C.

I think C too... As its a large dose of insulin, pt is likely to get hypoglycemic, hence the other hormones ll increase in response to hypoglycemia..!!
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Quote:
Originally Posted by pass7 View Post
i too thought it would decrease and the answer E????
I think you misread the question: "in response to the insulin injection?"

What happens to counter the actions of insulin is what it's asking...
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Old 06-26-2011
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Can someone please explain this in detail...I don't get why all the stress hormones hormones would increase to counteract insulin.
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Quote:
Originally Posted by heights View Post
Can someone please explain this in detail...I don't get why all the stress hormones hormones would increase to counteract insulin.
when you have hypoglycemia, the stress hormones will promote lipolysis, glycolysis etc. increased HR etc etc, to counteract the body from going into hypoglycemia. Its just an homeostasis mechanism to balance hypoglycemia and hyperglycemia.

Nothing more!
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Old 06-26-2011
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well i was thinking a but i guess the injectable insulin makes sense and then probably the idea of the response of the stress hormones too..so whats the final verdict...?
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I will go with C also
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E cuz i think it will take sometime fro all the stress hormones to kick in but the 1st action will be as e
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Thumbs Up correct answer

The correct answer is C)

Injection of Insulin leads to a decrease in blood glucose concentration. Hypoglycemia stimulates the secretion of growth hormone, glucagon, and epinephrine, all of with have counter regulatory effects to increase glucose levels in the blood.
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