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Old 09-03-2014
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Arrow Practice Question #3

A child has mononucleosis-like symptoms yet the test for mononucleosis
and the EBV titers are negative.
Which of the following is most likely the cause of heterophilenegative
mononucleosis?

(A) Cytomegalovirus
(B) Herpes simplex virus
(C) Varicella-zoster virus
(D) Adenovirus
(E) Coxsackievirus
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Old 09-03-2014
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A CMV can also cause mononucleosis but heterophile will be negative
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Old 09-03-2014
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Quote:
Originally Posted by Dr.ann View Post
A CMV can also cause mononucleosis but heterophile will be negative
Yep
Good Job!
The answer is A
Infectious mononucleosis caused by cytomegalovirus (CMV) is clinically difficult to distinguish from that caused by Epstein-Barr virus. Lymphocytosis is usually present with an abundance of atypical lymphocytes. CMV-induced mononucleosis should be considered in any case of mononucleosis that is heterophil-negative and in patients with fever of unknown origin.
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