The danger of Naloxone in a psychotic patient! - USMLE Forums
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Old 06-28-2011
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Drug The danger of Naloxone in a psychotic patient!

Naloxone would be contraindicated in an apparently psychotic patient if one were to also discover which of the following?
(A) The patient had a psilocybin-induced psychosis.
(B) The patient has hypertension.
(C) The patient has just suffered a fracture.
(D) The patient is a placebo responder.
(E) The patient is an alcohol abuser.
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Old 06-28-2011
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what in the world is a psilocybin induced psychosis???
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Old 06-28-2011
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Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action..
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Old 06-28-2011
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so what' the answer? maybe it's hypertension as morphine will cause hypotension so naloxane do the opposite?
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Old 06-28-2011
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Quote:
Originally Posted by dr_lizard View Post
so what' the answer? maybe it's hypertension as morphine will cause hypotension so naloxane do the opposite?
Nalaxone only blocks the receptor, it doesnt potentiate.. I think
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Old 06-28-2011
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so what is the answer saintdizzy?
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Old 06-28-2011
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Correct Answer The answer is C

Cos the patient with a fracture will be on an opiate based pain killer e.g morphine. Morphine inhibits morphine
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Old 06-29-2011
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Great question, pure logic...
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