u world questions:confusion regarding cortisol administration and T3 thyroide hormone administration. - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
USMLE Articles
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam

Thread Tools Search this Thread Display Modes
Old 07-03-2011
USMLE Forums Scout
Steps History: Not yet
Posts: 83
Threads: 23
Thanked 23 Times in 15 Posts
Reputation: 33
Question u world questions:confusion regarding cortisol administration and T3 thyroide hormone administration.

I was solving uworld questions and i met 2 question with similar concept and got confused

1) a case of a SLE on cortisol treatment undergoing surgery: so i understood that it is adrenal insufficiency due to prolonged cortisol treatment
so due to cortisol treatment: decreased CRH, decreased ACTH, and hence decreased cortisol.
suddenly i got confused and i thot since he is recieving cortisol his cortisol levels should be high..
so i marked increased cortisol decreased CRH and decresed ACTH option and it was wrong
2) another question was a hypothyroid symptom presentation recieving T3 thyroid hormone supplement:
the answer was : decreased TSH, incresed T3, reverse T3 no change,T4 no change.

so now i am confused...
can some1 explain to me: y is this two similar situation with similar exogenous administration but a deccreased cortisol with administration and increased T3 with T3 administration

but then i satisfied my self saying that because it is adrenal insufficiency and probably the treatment would have stopped and hence the low cortiol level...am i right?
Reply With Quote Quick reply to this message
The above post was thanked by:
Mashee (07-03-2011)

Old 07-03-2011
laithbv's Avatar
USMLE Forums Guru
Steps History: 1 + CS
Posts: 304
Threads: 9
Thanked 311 Times in 136 Posts
Reputation: 321

When you measure the cortisol level, you measure the "endogenous" cortisol level (which is suppressed) you don't measure the exogenous cortisone level.

In case of thyroid, T3 measurement will reflect the exogenous administration, it's the same compound (endogenous and exogenous).
Reply With Quote Quick reply to this message
The above post was thanked by:
drHubaishi (07-06-2014), Eric Zhuang (07-08-2011), jahn77 (07-03-2011), Mashee (07-03-2011), nevillenic (07-04-2011), winner21 (07-04-2011)


Endocrine-, Physiology-

Quick Reply

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Please enter a password for your user account. Note that passwords are case-sensitive.
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Where you live. Leave blank if you don't want to tell.


Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Cortisol Effects on Bones struggle USMLE Step 1 Forum 12 11-28-2014 11:15 AM
Three Questions about USMLE World Lara USMLE Step 1 Forum 3 02-04-2011 08:13 AM
USMLE World; Should we do all questions? MedicalDR14 USMLE Step 1 Forum 5 11-19-2010 08:18 AM
How many USMLE World Questions Per day usmle0987 USMLE Step 1 Forum 2 10-08-2010 01:14 PM
U world or free questions? DocSDH USMLE Step 1 Forum 8 06-29-2010 05:30 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)