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  #1  
Old 09-24-2014
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Default Reasoning for the Day

Patients of Bruton's agammaglobulinemia have impaired humoral immunity but they have intact cell-mediated immunity. That is why they have increased risk of infection to Staph and Strep but normal response to Listeria, Viruses and Fungi.

Why is there a normal response to Listeria?
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Old 09-25-2014
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Normal response to listeria meant there is no risk of listeria infection.. I think u want to say that?
If thats the case then i think in order to eliminate listeria we need intact cell mediated immunity and if thats intact no listeria infection thats what u mentioned above.
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Old 09-25-2014
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Default Listeria

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Originally Posted by Dr.ann View Post
Normal response to listeria meant there is no risk of listeria infection.. I think u want to say that?
If thats the case then i think in order to eliminate listeria we need intact cell mediated immunity and if thats intact no listeria infection thats what u mentioned above.
Specifically wanted to ask despite being normal bacteria "Why listeria needs a Cell-mediated immunity" like Fungi and Viruses to have normal response(defense) whereas other bacteria do not need Cell-mediated immunity?
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Old 09-25-2014
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Because listeria is a facultative intracellular bacteria!
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Old 09-25-2014
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Default Going good

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Because listeria is a facultative intracellular bacteria!
excellence, you are on the right path but you can explain more.
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Old 09-25-2014
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Because its the facultative intracellular organism.
It needs T cell mediated response in order to activate macrophages by IFN-gamma. And these steps is crucial for listeria killing!!
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Old 09-25-2014
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Default Dr. ann is right

Yes intracellular microbes need T cell mediated response
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Old 09-25-2014
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I would say as dr.ann!
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