Nitroglycerine Veno or Arteriolo Dilator! - USMLE Forums
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Old 07-10-2011
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Drug Nitroglycerine Veno or Arteriolo Dilator!

Nitroglycerine is a venodilator
The classic headache of nitroglycerine is caused by dilation of middle meningeal artery (But it is supposed to be a venodilator )
Nitroglycerine relieves angina pectoris by reducing preload by dilating venous return thus reducing oxygen demand of heart. (i thought it worked by dilating coronary vessels thereby improving oxygen consumption of myocardium)
All these are correct or am i wrong?
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Old 07-10-2011
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Nitroglycerine is venodilator> arteriodilator...its not comletely restricted to one function but it serves two function simply one more than other...
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Old 07-11-2011
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nitroglycerine at low doses causes venodilation---reduces preload by reducing venous return...
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Old 07-11-2011
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At high doses,nitrates cause arteriolar dilatation--------> decrease afterload--------> decrease cardiac oxygen demand !!!
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Cardiovascular-, Pharmacology-, Physiology-

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