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  #1  
Old 07-15-2011
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Kidney Bone Morphogenic Protein!

A 36-year-old mother took an experimental drug for morning sickness while she was pregnant. Several years later, this experimental drug is found to be a toxic agent that disturbs normal fetal development of the loop of Henle. Which of the following regulatory factors may contribute to this drug’s toxic side effect?


A. Bone morphogenic protein-4
B. Bone morphogenic protein-7
C. Bone morphogenic protein-3
D. Bone morphogenic protein-6
E. Bone morphogenic protein-5
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Old 07-15-2011
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pls give the answer soon with explanation I've absolutely no idea
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Old 07-15-2011
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Default ans

Quote:
Originally Posted by qurat21 View Post
pls give the ans soon with xplanation ve absolutely no idea
this is creepy question,never mind

The correct answer is B.

The loop of Henle is derived from the metanephric mesoderm. Development of the metanephric mesoderm is regulated by FGF-2 (fibroblast growth factor), BMP-7 (bone morphogenetic protein), and Wnt-11. GDNF (glial cell line-derived neurotrophic factor), WT-1 (an anti-oncogene), and c-Ret (tyrosine kinase receptor) regulate growth of the ureteric bud.
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Old 07-15-2011
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Quote:
Originally Posted by drgsarunprasath View Post
this is creepy question,never mind




The correct answer is B.

The loop of Henle is derived from the metanephric mesoderm. Development of the metanephric mesoderm is regulated by FGF-2 (fibroblast growth factor), BMP-7 (bone morphogenetic protein), and Wnt-11. GDNF (glial cell line-derived neurotrophic factor), WT-1 (an anti-oncogene), and c-Ret (tyrosine kinase receptor) regulate growth of the ureteric bud.
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Old 07-15-2011
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i didnt hear about these things at all!!
which q bank u seen this question?
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Old 07-15-2011
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wow! panic attack didnt know what bmp was till today! lol
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Old 07-16-2011
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Default kinda weird question,this is too much for us

Quote:
Originally Posted by dr_lizard View Post
i didnt hear about these things at all!!
which q bank u seen this question?
just wanted to share since it was too weird,

It was from Gunnertraining.com
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Old 01-14-2012
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You can read more about BMP from this medscape page

http://www.medscape.com/viewarticle/446738
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