Bacterial factor involved in a disease that caused sore throat then joint pain! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 07-17-2011
USMLE Forums Master
 
Steps History: Not yet
Posts: 674
Threads: 264
Thanked 959 Times in 393 Posts
Reputation: 969
Send a message via Yahoo to ricko335
Bacteria Bacterial factor involved in a disease that caused sore throat then joint pain!

Two weeks after having a sore throat and fever, a seven-year-old boy complains of knee pain, elbow pain, and chest pain. Physical examination demonstrates a macular rash on his trunk. What bacterial factor is involved in this disease?
A. SpeA
B. Polysaccharide capsule
C. SpeC
D. Lipopolysaccharide
E. M-protein
Reply With Quote Quick reply to this message



  #2  
Old 07-17-2011
Banned
 
Steps History: 1 + CS
Posts: 33
Threads: 4
Thanked 33 Times in 10 Posts
Reputation: 43
Default

scarlet fever - m protein
Reply With Quote Quick reply to this message
  #3  
Old 07-18-2011
axax's Avatar
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 115
Threads: 3
Thanked 266 Times in 41 Posts
Reputation: 276
Default

E. M-protein
__________________
Learning is like to row your boat upstream, if you stop learning, you will be pushed back by the current.
Reply With Quote Quick reply to this message
  #4  
Old 07-18-2011
dr.digant's Avatar
USMLE Forums Addict
 
Steps History: Step 1 Only
Posts: 127
Threads: 21
Thanked 103 Times in 53 Posts
Reputation: 113
Default

Quote:
Originally Posted by drsmart View Post
scarlet fever - m protein
its not scarlet fever..its rheumatic fever...the rash is erythema marginatum....scarlet fever is caused by erythrogenic toxin..
Reply With Quote Quick reply to this message
  #5  
Old 07-18-2011
Banned
 
Steps History: 1 + CS
Posts: 33
Threads: 4
Thanked 33 Times in 10 Posts
Reputation: 43
Default

sorry boss, your the expert thanks for making me feel good about it
Reply With Quote Quick reply to this message
  #6  
Old 07-18-2011
USMLE Forums Master
 
Steps History: Not yet
Posts: 674
Threads: 264
Thanked 959 Times in 393 Posts
Reputation: 969
Send a message via Yahoo to ricko335
Default answer

M Protein
Rheumatic fever is mediated by antibodies against S. pyogenes M-protein, making it an autoimmune disease. The major JONES criteria for diagnosis of rheumatic fever are carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. Carditis can present as pericarditis, which would cause chest pain. The polyarthritis can occur in up to 80% of patients and most commonly involves multiple large joints. The rash and subcutaneous nodules are rare findings, and Sydenham’s chorea occurs late in rheumatic fever
Reply With Quote Quick reply to this message
The above post was thanked by:
dr_lizard (08-24-2011), monsalg2502 (09-15-2011)
  #7  
Old 07-18-2011
USMLE Forums Master
 
Steps History: Not yet
Posts: 674
Threads: 264
Thanked 959 Times in 393 Posts
Reputation: 969
Send a message via Yahoo to ricko335
Thumbs Up always remember this

S. pyogenes causes:
• Pharyngitis (“Strep throat”)
• Impetigo
• Erysipelas/cellulitis

Toxin-mediated disease:
• Scarlet fever
• TSLS (toxic shock-like syndrome)
• Necrotizing fasciitis

Autoimmune disease:
• Rheumatic fever (type 2 hypersensitivity)
• Post-strep glomerulonephritis (type 3 hypersensitivity)

S. pyogenes: β-hemolytic, bacitracin-sensitive, hyaluronic acid capsule (antiphagocytic), M protein (inhibits opsonization)—3 toxins, 4 enzymes:

3 toxins—
1) Erythrogenic toxin (superantigen) → Scarlet fever
2) Pyogenic exotoxin A (superantigen) → Strep TSLS
3) Exotoxin B (protease) → Necrotizing fasciitis

4 enzymes—
1) Hyaluronidase → facilitates spread through tissue (cellulitis)
2) Streptokinase (fibrinolysin)
3) Streptolysin O: oxygen-labile, β-hemolytic, antigenic (Anti-Streptolysin O (ASO) titer is important for Dx Rheumatic fever)
4) Streptolysin S: oxygen-stable, β-hemolytic, not antigenic
Reply With Quote Quick reply to this message
The above post was thanked by:
Cal_Tina (01-12-2012), donofitaly (07-18-2011), dr_lizard (08-24-2011), m82_ghasemi (08-24-2011), monsalg2502 (09-15-2011), pass7 (07-19-2011)
  #8  
Old 09-14-2012
billy's Avatar
USMLE Forums Guru
 
Steps History: Not yet
Posts: 444
Threads: 109
Thanked 369 Times in 208 Posts
Reputation: 379
Thumbs Up ...

Yes its M Protein
Reply With Quote Quick reply to this message



Reply

Tags
Microbiology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Heart Disease Risk Factor Question INCOGNITO USMLE Step 1 Forum 7 09-14-2012 07:37 AM
A 5 year old boy with fever,soar throat and swollen lymph nodes aksyonez USMLE Step 2 CK Forum 3 07-06-2011 05:51 PM
55 yo man with monoarthritis of knee joint tkourkou USMLE Step 2 CK Forum 7 03-15-2011 04:26 PM
A young man with fever, sore throat and rash 1TA2B USMLE Step 2 CK Forum 7 03-14-2011 10:34 AM
Which vessel is involved! sam01 USMLE Step 1 Forum 4 07-06-2010 10:53 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)