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Old 07-17-2011
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Drug Influenza virion particles are still there despite improvement!

A patient with severe influenza A pneumonia is treated with an antiviral medication. Three days after initiation of treatment, a sample of his epithelial cells is studied. A significant portion of the cells are packed with virion particles but the patient has clinically improved. Which medication was he prescribed?

A. Delavirdine
B. Peramivir
C. Ribavirin
D. Foscarnet
E. Amantadine
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Old 07-18-2011
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E. Amantadine- it prevents the uncoting of the virus into the host cells
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Old 07-18-2011
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I agree

Quote:
Originally Posted by ricko335 View Post
A patient with severe influenza A pneumonia is treated with an antiviral medication. Three days after initiation of treatment, a sample of his epithelial cells is studied. A significant portion of the cells are packed with virion particles but the patient has clinically improved. Which medication was he prescribed?

A. Delavirdine
B. Peramivir
C. Ribavirin
D. Foscarnet
E. Amantadine
its ribavirin..becoz there are alreaady viral particle inside cell...so drug that prevent viral uncoating will not helpful...ribavirin inhibit viral RNA POLYMERASE...and infuenza is negetive stranded virus it will not replicate witout help of RNA POYMERASE....
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Old 07-18-2011
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Amandine..because once the virus penetrates inside the cell ,it block the uncoating of the virus.The protein synthesis and other streps occur after this step so the best answer would be AMANTADINE.
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Old 07-18-2011
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The correct answer is B.
To release viral progeny, influenza uses neuraminidase to cleave cell membrane structures. Neuraminidase inhibitors like oseltamivir, zanamivir and peramivir prevent this from happening, leading to infected cells being packed with virion particles since viral replication isnít inhibited
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