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#1
07-17-2011
 USMLE Forums Addict Steps History: 1 + CK Posts: 197 Threads: 51 Thanked 93 Times in 35 Posts Reputation: 103
biostat Hardy weinberg question

In a clinical study of 100 subjects...for a gene related to bladder cancer
genotype NO.of controls
AA 45
BB 30
AB 25

if A n B are both one allele each..wsich is frequency of allele A ?

a-115/200
b-90/200
c-50/200
d-25/200
e-45/200

plz...ans biostat for me is a headche!!!!!
 The above post was thanked by: dr_lizard (09-05-2011), Mashee (07-17-2011), SuperGirl28 (09-11-2013), usluipek (07-17-2011)

#2
07-17-2011
 USMLE Forums Guru Steps History: Step 1 Only Posts: 343 Threads: 127 Thanked 525 Times in 192 Posts Reputation: 535

we have to calculate fq of allele A
in first row AA = 45*2=90
then in third row A= 25
total A= 115
and devided by total no. of all alleles like 90+60+50= 200
hope it wil help u out..
 The above post was thanked by: dr.dhruvdesai (07-17-2011), Mashee (07-17-2011), SuperGirl28 (09-11-2013), usluipek (07-17-2011)
#3
07-17-2011
 USMLE Forums Guru Steps History: Step 1 Only Posts: 326 Threads: 20 Thanked 220 Times in 124 Posts Reputation: 232
it is NBME - 3

Please, do not post questions from NBME, because when people go to check their performance online, seeing this questions and answers would affect their outcome. It is very critical point!!!

Correct answer for question seen first time - means "You know the concept!"

Correct answer for question already seen somewhere....is not correct, just knowing the answer, it is not the goal of preparation.

Thank you for understanding!
 The above post was thanked by: usluipek (07-17-2011)

#4
07-18-2011
 USMLE Forums Addict Steps History: 1 + CK Posts: 197 Threads: 51 Thanked 93 Times in 35 Posts Reputation: 103

sorry sir, but this must be a similar question.its from one of the 4tests.com...it allows discussion of its questions in forums.its nice check it out.
 The above post was thanked by: Mashee (07-18-2011)

 Tags Biostatistics-Epidemiology, Step-1-Questions

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