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  #1  
Old 07-19-2011
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I agree 56-year-old man who died suddenly

This segment of the arterial intima of a coronary vessel is observed at autopsy in a 56-year-old man who died suddenly on rising in the morning. Which of the following abnormalities is considered a major risk factor for the development of this lesion?

56-year-old man who died suddenly-cardio_v.png

(A) Congenital vascular muscle weakness
(B) Cystic medial necrosis
(C) Hypercholesterolemia
(D) Medial calcification
(E) Syphilis
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Old 07-19-2011
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i'll go with option C..

A) ... ? No idea at this moment
B) Aortic Disection ( Aorta ) Pain radiating to the back
D) Mockenberg which is asymptomatic and generally dont block the lumen and some cases block radial or ulnar artery.
E) Vasa vasorum of aorta...
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Old 07-19-2011
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And,, Maybe it could be Aortic Dissection, because of the Dystrophic calcification... Which is a hallmark preceding the cell injury ... which shows deposit of purple, white granules and harp Edge...

So my options are narrow to B ( Hipercholesterolemia which leads to arterosclerosis which leat to Aneurysm of the coronary ... which can ruptur and DEAD!! ) or C.

Last edited by rulz; 07-19-2011 at 12:45 PM.
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Old 07-19-2011
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(C) Hypercholesterolemia-arteriosclerosis- rupture!
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Ruling out the options i guess my answer is hypercholestrolemia

Cystic medial necrosis : degeneration of collagen and elastic fibers in the tunica media of the aorta, as well as the loss of medial cells that are replaced by multiple clefts of mucoid material.

Syphillis: This condition results in uncomplicated aortitis, aortic regurgitation, saccular aneurysm (usually of the ascending aorta), or coronary ostial stenosis.
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Old 07-19-2011
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I think its C cuz these elongated lesions are ones in cholesterol
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Old 07-19-2011
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Correct Answer Correct answer

The answer is C.

The figure shows a segment of a large atheromatous plaque. The clinical scenario strongly suggests that this affected vessel is a coronary artery. Cleft-like spaces indicating the presence of cholesterol crystals are very prominent and help in the identification of the lesion. The incidence of atherosclerosis is strongly associated with hypercholesterolemia.
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