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  #1  
Old 08-02-2011
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Lungs Most common cancer due to Asbestos!

The most common cancer in people exposed to asbestos is
a) adenocarcinoma
b) Small cell carcinoma
c) Squamous cell carcinoma
d) Mesothelioma
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Small Cell Carcinoma
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Old 08-02-2011
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mesothelioma...
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Old 08-02-2011
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asbestosis leads to mesothelioma

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Old 08-02-2011
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squamous cell Ca
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C Squamous Cell
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Squamous then Mesothelioma

Small was most often due to cigarettes without filters & cubano's.
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Mesothelioma....results in haemorrhagic pleural effusion and pleural thickening
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MCC = Squamous cell carcinoma (takes less time!) >> Mesothelioma
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Correct Answer The answer is C

Most people once they see asbestos, they gravitate towards mesothelioma.
MCC is still squamous cell
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  #11  
Old 08-02-2011
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Default D

d)Mesothelioma
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the answer is d
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  #13  
Old 09-09-2011
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Warning! Asbestosis and Cancer

Quote:
Originally Posted by saintdizzy View Post
Most people once they see asbestos, they gravitate towards mesothelioma.
MCC is still squamous cell
Look at this site:

http://www.cancer.gov/cancertopics/f.../Risk/asbestos

"Although rare, mesothelioma is the most common form of cancer associated with asbestos exposure." SO D is correct.

OR

http://en.wikipedia.org/wiki/Mesothelioma

Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers, Those who have been exposed to asbestos have collected damages for asbestos-related disease, including mesothelioma.

OR

http://www.allaboutmalignantmesothel...s-exposure.htm
Pleural Mesothelioma - The Most Common Cancer Linked to Asbestos Exposure
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Old 09-09-2011
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Quote:
Originally Posted by m82_ghasemi View Post
Look at this site:

http://www.cancer.gov/cancertopics/f.../Risk/asbestos

"Although rare, mesothelioma is the most common form of cancer associated with asbestos exposure." SO D is correct.

OR

http://en.wikipedia.org/wiki/Mesothelioma

Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers, Those who have been exposed to asbestos have collected damages for asbestos-related disease, including mesothelioma.

OR

http://www.allaboutmalignantmesothel...s-exposure.htm
Pleural Mesothelioma - The Most Common Cancer Linked to Asbestos Exposure
I think if you google "Most common cancer" "asbestos", you will get both answers as the MCC.
But, if you read Kaplan and RR Pathology (goljan book & audio), both say Lung cancer...so, I think the better answer is C) (for the purposes of the USMLE)
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  #15  
Old 09-10-2011
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mESOTHELIOMA!!
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Old 09-10-2011
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Default Source?

Quote:
Originally Posted by saintdizzy View Post
Most people once they see asbestos, they gravitate towards mesothelioma.
MCC is still squamous cell
Can u plz mention the source?.......thanks !
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  #17  
Old 09-10-2011
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Quote:
Originally Posted by tangled View Post
Can u plz mention the source?.......thanks !
check RR Pathology (Goljan - last edition), chapter 16.
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  #18  
Old 09-10-2011
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SCC is the answer....mesothilioma is found most common in people with asbestos exposure
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  #19  
Old 04-21-2012
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Lungs Asbestosis most common type of lung CA?

what the most likely cancer to result from asbestose exposure as in FA it says mesothelioma , while uworld says it is bronchogenic CA
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Old 04-21-2012
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Goljan says its bronchogenic CA........i believe in him..!!!!
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Old 04-21-2012
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Quote:
Originally Posted by flowerlady1 View Post
what the most likely cancer to result from asbestose exposure as in FA it says mesothelioma , whille uworld says it is bronchogenic CA
i would look for both in answer
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Old 04-21-2012
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http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001177/

According to pubmed, it is mesothelioma. Hope that this helps.
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Old 04-21-2012
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Mesothelioma
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  #24  
Old 04-21-2012
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it causes both bronchogenic and mesthiloma, they wont ask you which one is more common i think, but they might ask you what if the patient is smoking then smoking + asbest = 10000000% of bronchogenic carcinoma.
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the most common cancer is squamous cell carcinoma of lung............Mesothelioma if patient is a smooker.The most recent lecture from Kaplan stressed specially on this that Mesothelioma as the most common cancer after esbestos exposure is a wrong answer.
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Old 04-21-2012
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i think from kaplan i learned that the most common is brochiogenic carcinoma, not mesothelioma.

but which (small cell, squamous, adeno, etc) is most common i'm not sure.

whats the answer?
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You are right...I double checked it.It says 70% bronchogenic Ca( Squamous cell Ca and adenocarcinoma
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Old 04-22-2012
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The reason that SCC is the answer, is because the incidence of SCC in the general population is greater than the incidence of mesothelioma (even in those who have been exposed to asbestos)

It's a bit of a trick question. Sure asbestos exposure increases risk greatly for mesothelioma, however it doesnt guarantee you will get mesothelioma. the incidence of mesothelioma in people exposed to asbestos is still tiny compared to incidence of SCC.

http://www.ncbi.nlm.nih.gov/pubmed/10076559
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Old 04-22-2012
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Mesothelioma for sure
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Dr Sattar in Pathoma says its the bronchogenic form of squamus cell carcinoma.. and he insists that its more common that mesothelioma
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Old 04-23-2012
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Default As the Summary

So it's quite clear that different sources say different stuff.

Dr.Goljan RR - MC after asbestos exposure is Primary Lung Cancer, the book doesn't say which of it.
Dr.Sattar Pathoma - is actually saying the same thing.
NCBI - Pubmed -> tell that Mesothelioma is the MC.
I also mailed the admin if the website pathologystudent.com and the answer was as follows:

"As far as lung cancers related to asbestos, mesothelioma is the most common (if you're calling it a lung cancer). 70% of all mesotheliomas are directly related to asbestos exposure. Asbestos is also related to primary lung carcinomas - but those are not nearly as common as asbestos-related mesotheliomas." - says Krisine Krafts MD.

Another source www.asbestos.net the web site which has very reliable information about mesotheliomas and lung cancers.
Quotes from the asbestos.net:

" Asbestos Cancer: Mesothelioma
Malignant Mesothelioma While relatively rare, with between 2000 and 3000 new cases reported in the U.S. each year, malignant mesothelioma is still a significant risk to people exposed to asbestos. Because mesothelioma symptoms are similar to those of other diseases, and because the disease can take 40 years or more to manifest after asbestos exposure, there is some concern about misdiagnosed mesothelioma cases and questions as to whether this asbestos cancer is underreported. However, it is agreed that asbestos exposure is the primary cause; in almost all cases, patients who are diagnosed with mesothelioma have been exposed to asbestos in the past."

The next one:

"Asbestos Related Lung Cancer
The average man in the U.S. has a one in 12 chance of getting lung cancer and the average woman a one in 16 chance. Asbestos workers, however, are about seven times more likely to die of lung cancer than people in general. Asbestos workers who smoke have a 50 to 90 times greater chance of getting lung cancer than the general population"

" Non-small cell lung cancer (NSCLC) accounts for 85% to 90% of all lung cancers. Asbestos exposure in the workplace, along with other environmental factors, is a risk factor for NSCLC.

Small cell lung cancer (SCLC) makes up the remaining 10% to 15% of lung cancers. As in non-small cell lung cancer, asbestos exposure is a significant risk factor. Apart from mesothelioma, most asbestos-related lung cancers belong to the SCLC category."

this video may be helpfull:
http://www.youtube.com/watch?feature...&v=kDDij9tRuwY




Summary: Mesothelioma is in most cases associated with asbestos exposure, but the patient is more likley to have primary lung cancer. I think Goljan has a point, he says that primary lung cancer development takes 10 years (appr), mesothelioma takes about 25-30 years. + to all this smoking + asbestos increases risk for primary lung cancer, but it doesn't increase the risk of mesothelioma. So it is more likley The PATIENT WHO IS EXPOSED TO ASBESTOS TO HAVE PRIMARY LUNG CANCER MORE THAN MESOTHELIOMA.
another question is, which of the primary lung cancers?
non small cell cancers are seen in 85% of cases. and Of the primary lung carcinomas, adenocarcinoma is the most common (42% of cases), then squamous cell carcinoma (28%), then small cell carcinoma (16%), and finally large cell carcinoma (14%). I conclude that Primary Lung cancer is the Most common cancer associated with asbestos. not sure about which of them SCC or adenocarcinoma ? .... i would go for SCC.
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  #32  
Old 04-23-2012
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Quote:
Originally Posted by beka-CTS View Post
So it's quite clear that different sources say different stuff.

Dr.Goljan RR - MC after asbestos exposure is Primary Lung Cancer, the book doesn't say which of it.
Dr.Sattar Pathoma - is actually saying the same thing.
NCBI - Pubmed -> tell that Mesothelioma is the MC.
I also mailed the admin if the website pathologystudent.com and the answer was as follows:

"As far as lung cancers related to asbestos, mesothelioma is the most common (if you're calling it a lung cancer). 70% of all mesotheliomas are directly related to asbestos exposure. Asbestos is also related to primary lung carcinomas - but those are not nearly as common as asbestos-related mesotheliomas." - says Krisine Krafts MD.

Another source www.asbestos.net the web site which has very reliable information about mesotheliomas and lung cancers.
Quotes from the asbestos.net:

" Asbestos Cancer: Mesothelioma
Malignant Mesothelioma While relatively rare, with between 2000 and 3000 new cases reported in the U.S. each year, malignant mesothelioma is still a significant risk to people exposed to asbestos. Because mesothelioma symptoms are similar to those of other diseases, and because the disease can take 40 years or more to manifest after asbestos exposure, there is some concern about misdiagnosed mesothelioma cases and questions as to whether this asbestos cancer is underreported. However, it is agreed that asbestos exposure is the primary cause; in almost all cases, patients who are diagnosed with mesothelioma have been exposed to asbestos in the past."

The next one:

"Asbestos Related Lung Cancer
The average man in the U.S. has a one in 12 chance of getting lung cancer and the average woman a one in 16 chance. Asbestos workers, however, are about seven times more likely to die of lung cancer than people in general. Asbestos workers who smoke have a 50 to 90 times greater chance of getting lung cancer than the general population"

" Non-small cell lung cancer (NSCLC) accounts for 85% to 90% of all lung cancers. Asbestos exposure in the workplace, along with other environmental factors, is a risk factor for NSCLC.

Small cell lung cancer (SCLC) makes up the remaining 10% to 15% of lung cancers. As in non-small cell lung cancer, asbestos exposure is a significant risk factor. Apart from mesothelioma, most asbestos-related lung cancers belong to the SCLC category."

this video may be helpfull:
http://www.youtube.com/watch?feature...&v=kDDij9tRuwY




Summary: Mesothelioma is in most cases associated with asbestos exposure, but the patient is more likley to have primary lung cancer. I think Goljan has a point, he says that primary lung cancer development takes 10 years (appr), mesothelioma takes about 25-30 years. + to all this smoking + asbestos increases risk for primary lung cancer, but it doesn't increase the risk of mesothelioma. So it is more likley The PATIENT WHO IS EXPOSED TO ASBESTOS TO HAVE PRIMARY LUNG CANCER MORE THAN MESOTHELIOMA.
another question is, which of the primary lung cancers?
non small cell cancers are seen in 85% of cases. and Of the primary lung carcinomas, adenocarcinoma is the most common (42% of cases), then squamous cell carcinoma (28%), then small cell carcinoma (16%), and finally large cell carcinoma (14%). I conclude that Primary Lung cancer is the Most common cancer associated with asbestos. not sure about which of them SCC or adenocarcinoma ? .... i would go for SCC.
but Kaplan live lectures stressed it so much that its bronchogenic CA not mesothelioma! they repeated asked us again and again to drill it in our heads.
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Old 04-23-2012
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Default its SCC

enough with all the HiFi resources links all of u hv quoted...

its plain simple....

this question s frm uworld..

the ans given is Sq.cell ca PERIOD
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Old 04-28-2012
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so i just did a uworld question and it asked the most common lung tumor.

The answer they gave was Adenocarcinoma.

They have a little table in the explaination that shows the occurance of each type of lung cancer. Both adenocarcinoma and squamous cell both are indicated 25-40% of the time. However in this question it said the patient doesn't smoke, so in that case adeno is more likely than squamous.

so adenocarcinoma and squamous cell carcinoma are the most common forms of lung cancer. The former in a nonsmoker, and the latter in a smoker.

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Old 05-14-2012
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Correct Answer The answer is C

Here is my take on it.

Exposure to asbestos is present in over 90% of mesothelioma cases. However, mesothelioma in itself is very rare to begin with. Plus people exposed to asbestos are MOST likely to get lung cancer.

So, in most cases of mesothelioma, the cause is asbestos.

In most cases of asbestos exposure, the result is lung cancer.

The answer is C. Hope that helps.
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  #36  
Old 08-27-2012
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Disease is caused by smoking or asbestos, lung cancer symptoms are the same.


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