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  #1  
Old 08-04-2011
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RBC The cause of jaundice in Thalassemia major

A 25 year old Mediterranean female with Thalassemia major presents with jaundice. The color of her stool and the color of her urine are normal. Upon laboratory tests she is found to have an unconjugated hyperbilirubinemia. Her peripheral blood smear shows a microcytic anemia as well as target cells. What is the likely cause of her jaundice?

a)
Rotor's Syndrome
b)
Primary biliary cirrhosis
c)
Gilbert's Syndrome
d)
Hepatitis B
e)
Hemolysis
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  #2  
Old 08-04-2011
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I think its hemolysis
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  #3  
Old 08-05-2011
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i'm also thinking hemolysis
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  #4  
Old 08-05-2011
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E its extravascular hemolysis by spleen :P
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Old 08-05-2011
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I disagree

E.hemolysis
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Old 08-05-2011
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E.Hemolysis
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Old 03-25-2012
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The answer should be E
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Old 03-25-2012
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Hemolysis.
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  #9  
Old 03-25-2012
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E. Hemolysis for sure. Remember in thalassemia RBC will get destroyed in the spleen more often than not.

Think CAST IRON.
  • Chronic Disease
  • Autoimmune (hemolysis)
  • Sideroblastosis
  • Thalassemia
  • Iron deficiency
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