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Old 08-11-2011
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Idea! clinical related Anatomy question

a CT cross section image of the thorax reveals an absence of an anterior mediastinum shadow in a patient diagnosed with the DiGeorge sequence. what else will be missing in the patient?
a. thyroid gland
b.palatine tonsil
c.malleus and incus
d.parathyroid gland
e.adrenal medulla
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jahn77 (08-11-2011)



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Old 08-11-2011
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d) parathyroid gland, as DiGeorge may be ass.with Ca exchange disorders, as well thymus is the same origin with parathyroid.
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Old 08-11-2011
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Problem of III and IV Pharyngeal Arches ( i.e. Neural Crest Cells to migrate)
Deffinetly answer is Parathyroid Glands.
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Old 08-11-2011
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you are so right ,, in DiGeorge sequence there is abscence of the parathyroid causing hypocalcemia as well as absence of the thymus and that what causes the absence of shadow in the anterior mediastinum and also causes that this person suffers from decrease in immunity
thanks so much
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