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Old 12-02-2014
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Default Blood Groups

Hello,
I understand that in trauma situations, we give type Blood Group O- (negative).
My question is that, do they remove the antibodies to Rh factor from the blood before the transfusion.

Thanks.
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Old 12-02-2014
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Firstly, People with Rh negative blood groups don't have very high titres of anti - Rh antibodies until exposed to Rh + blood.

Secondly, whole blood is rarely given now. We usually give packed cells. In any case, since antibodies are in plasma and a very small amount of that plasma from the donor blood is going into a much larger volume of plasma in the recipient, the antibodies will dilute and won't cause a reaction.

However, if you infuse Rh + blood into an Rh - patient, the recipient will develop an immune response and hemolysis of all those donated RBC's will occur, and he would have hemoglobinuria and all features of a hemolytic reaction, while rendering the transfusion useless, as the donated RBC's were destroyed.
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Old 12-02-2014
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Thank you so much, appreciate it.
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