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#1
08-15-2011
 USMLE Forums Master Steps History: Not yet Posts: 674 Threads: 264 Thanked 963 Times in 394 Posts Reputation: 973
Blood Alcohol Level after drinking!

After a night of alcohol drinking with friends, a college student asks when he should expect to regain sobriety. Which of the following statements is true?
A. There will be the highest decrease in blood ETOH in hour 1-2
B. There will be the highest decrease in blood ETH in hour 5-6
C. There is no mathematical correlation to determine blood ETOH elimination
D. The decrease in blood ETOH between hour 1-2 is same as hour 5-6
E. There will be a higher decrease in blood ETOH between hour 5-6 versus hr
 The above post was thanked by: usluipek (08-16-2011), usmleman2020 (08-15-2011)

#2
08-15-2011
 USMLE Forums Guru Steps History: Step 1 Only Posts: 326 Threads: 20 Thanked 220 Times in 124 Posts Reputation: 232

zero order so its D)but in chronic alcohol intake it may be different
#3
08-15-2011
 USMLE Forums Veteran Steps History: Not yet Posts: 258 Threads: 118 Thanked 294 Times in 115 Posts Reputation: 304

D. The decrease in blood ETOH between hour 1-2 is same as hour 5-6

#4
08-16-2011
 USMLE Forums Master Steps History: Not yet Posts: 674 Threads: 264 Thanked 963 Times in 394 Posts Reputation: 973

ETOH is eliminated through zero order kinetics. In this type of elimination, there is a constant amount of drug eliminated by unit time. Therefore, hours 1-2 will have the same amount of ETOH drug elimination as hours 5-6. By contrast, most drugs undergo a first order kinetics and will have a constant percentage of elimination through time.
 The above post was thanked by: usluipek (08-16-2011)

 Tags Pharmacology-, Step-1-Questions

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