Amilotropic Lateral Sclerosis: Mixed Lesion or Pure Motor Lesion? - USMLE Forums
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Old 08-16-2011
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Default Amilotropic Lateral Sclerosis: Mixed Lesion or Pure Motor Lesion?

In FA & Goljan and everywhere I've seen it says its a pure MOTOR lesion,

in UW questions (I dont know exactly which one, I wrote the answer down in my notes), it said:

"Combination of fixed segmental loss of upper extremity pain & temp sensation + lower extremity weakness and / or upper extremity weakness & hyporeflexia"

Which one do I trust?

It seems that there are many areas where UW doesn't agree with Goljan / UpToDate / FA.
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Arrow ALS

UW can be strange sometimes..I used the search function to search for ALS, Amyotrophic Lateral Sclerosis and Lateral Sclerosis and there were only two questions that showed up -


Ques ID 1904: Choice A = ALS
It states that "ALS is a progressive degenerative disease of upper and lower motor neurons only; it does not cause sensory loss."

Ques ID 672: Choice E = Loss of neurons in the anterior horn of spinal cord
It states that this "[Choice E] occurs in poliomyelitis and leads to flaccid paralysis, atrophy, areflexia & muscle fasciculation. Damage to these neurons also occurs in ALS."
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Quote:
Originally Posted by Hope2Pass View Post
UW can be strange sometimes..I used the search function to search for ALS, Amyotrophic Lateral Sclerosis and Lateral Sclerosis and there were only two questions that showed up -


Ques ID 1904: Choice A = ALS
It states that "ALS is a progressive degenerative disease of upper and lower motor neurons only; it does not cause sensory loss."

Ques ID 672: Choice E = Loss of neurons in the anterior horn of spinal cord
It states that this "[Choice E] occurs in poliomyelitis and leads to flaccid paralysis, atrophy, areflexia & muscle fasciculation. Damage to these neurons also occurs in ALS."
Yea, you're right.

It was Question 1904, I musta written about something else afterwards, perhaps polio.
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hm, yea. But it seems like its a pure Motor lesion of upper and lower motor neurons.
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Quote:
Originally Posted by patelMD View Post
In FA & Goljan and everywhere I've seen it says its a pure MOTOR lesion,

in UW questions (I dont know exactly which one, I wrote the answer down in my notes), it said:

"Combination of fixed segmental loss of upper extremity pain & temp sensation + lower extremity weakness and / or upper extremity weakness & hyporeflexia"

Which one do I trust?

It seems that there are many areas where UW doesn't agree with Goljan / UpToDate / FA.
this sounds more like syringomyelia Like u said There must be have been some mix up some where along the line
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Originally Posted by ibukun View Post
this sounds more like syringomyelia Like u said There must be have been some mix up some where along the line
yeah, question 1904 .. the answer was syringiomyelia but choice A talked about ALS!
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