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Old 08-17-2011
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Default evolution of EPS effects

Hi all:

Can someone please tell me who is right?

In Kaplan, it says that the evolution of extrapyramidal effects:

after hours: pseudoparkisonism

after days: dystonia

however, in FA, it says

after hours: dystonia

after days: pseudoparkinsonism


so who is correct?
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Old 08-17-2011
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Quote:
Originally Posted by mbbs2010 View Post
pseudoparkinsonism is first

explain please.
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Old 08-18-2011
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the correct order is first dystonia then Parkinsonism

this error has been corrected in the latest kaplan book version
i spoke with dr davis (teaches at kaplan) today.

he said the reason for the side effect of dystonia was unknown but it was the first to develop and can develop even within 2 days of the drug being taken. presents with characteristic torticollis and upward gaze gyrating eye.

the Parkinsonism...etc can be explained by DA changes in the various other pathways in the brain. (pls let me know if u need explanations for these as well)
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Old 08-18-2011
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Quote:
Originally Posted by mbbs2010 View Post
the correct order is first dystonia then Parkinsonism

this error has been corrected in the latest kaplan book version
i spoke with dr davis (teaches at kaplan) today.

he said the reason for the side effect of dystonia was unknown but it was the first to develop and can develop even within 2 days of the drug being taken. presents with characteristic torticollis and upward gaze gyrating eye.

the Parkinsonism...etc can be explained by DA changes in the various other pathways in the brain. (pls let me know if u need explanations for these as well)
it would be beneficial if you could go over that too, if time avails. thanksss!
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Old 08-18-2011
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will be revising that topic tomorrow. post the explanation then.
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