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Old 08-18-2011
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Default interpret d labs

In which of the following diseases would you NOT expect to find the following lab values?
AST 8 U/L

ALT 10 U/L
Alkaline Phosphatase 230 U/L
A. Prostate cancer with metastases to bone
B. Osteitis deformans
C. Multiple myeloma with osteolytic lesions
D. Osteomalacia
E. Rickets
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Old 08-18-2011
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Must be MM. Option C.
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A. because Prostate Ca mets are usually osteoblastic (90%)
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Old 08-18-2011
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I guess c
prostate mets would have elevated alkaline phosphatase precisely because they are osteoblastic
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C. Multiple myeloma with osteolytic lesions
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Quote:
Originally Posted by patient doctor View Post
I guess c
prostate mets would have elevated alkaline phosphatase precisely because they are osteoblastic
Yes I can't believe, I was rolling on that thought, its meant to be the complete OPPOSITE.. thanks.. so i will go with.. C too
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Old 08-19-2011
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Correct Answer

The correct answer is C.
Alk phos is not elevated in multiple myeloma, even with osteolytic lesions. It is, however, ↑ in osteoblastic lesions (bone being built), such as in metastatic prostate cancer (this is a somewhat unique feature of prostate CA
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