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Old 08-19-2011
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Question secondary sexual characteristics and ovarian mass!

A couple brings in their 8-year-old daughter who is starting to develop secondary sexual characteristics. They are concerned that she is maturing too early. Examination shows an ovarian mass. Biopsy reveals small follicles filled with eosinophilic secretions. Which of the following is her most likely diagnosis?
A. Fibroma
B. Granulosa Cell Tumor
C. Brenner Tumor
D. Meig’s Syndrome
E. Mucinous cystadenoma
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Old 08-19-2011
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Default B?

i think its B, granulosa ...
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Old 08-19-2011
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Default B. gradulosa cell tumor

secondary sexual characteristics + call-exner bodies (esinophillic secretion)
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Old 02-21-2012
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Default

Great question!!!... Granulosa cell tumor, secretes estrogen, so that's why the little girl is developing sec. sexual characteristics so early/

But in the adults, is a risk factor first for endometrial hyperplasia, and after that carcinoma, because of the unopposed estrogen. Call - Exner bodies are the small follicles filled with the eosinophilic secretions.
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Old 02-21-2012
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B... small follicles filled with eosinophilic secretions + secondary sexual characteristics.
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