A couple brings in their 8-year-old daughter who is starting to develop secondary sexual characteristics. They are concerned that she is maturing too early. Examination shows an ovarian mass. Biopsy reveals small follicles filled with eosinophilic secretions. Which of the following is her most likely diagnosis?
A. Fibroma
B. Granulosa Cell Tumor
C. Brenner Tumor
D. Meig’s Syndrome
E. Mucinous cystadenoma
Great question!!!... Granulosa cell tumor, secretes estrogen, so that's why the little girl is developing sec. sexual characteristics so early/
But in the adults, is a risk factor first for endometrial hyperplasia, and after that carcinoma, because of the unopposed estrogen. Call - Exner bodies are the small follicles filled with the eosinophilic secretions.
B... small follicles filled with eosinophilic secretions + secondary sexual characteristics.
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