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Old 08-20-2011
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Drug Serious toxicity of anti-neoplastic drugs!

A 60-year-old woman comes to the physician because she recently was diagnosed with non-small cell lung carcinoma and she wants to discuss possible treatment options. She tells the physician that she is concerned about the possible adverse effects of chemotherapy. The physician says that serious toxicity caused by antineoplastic drugs is seen in the bone marrow. Which of the following best explains this finding?

(A) Cells in the marrow divide rapidly
(B) Cells in the marrow have specific surface targets for most of these drugs
(C) Cells in the marrow lack the enzymes to protect against the drugs
(D) Chemotherapy drugs act preferentially against cells with no nucleus
(E) Chemotherapy drugs penetrate well into the marrow because it is very vascular
(F) Chemotherapy drugs tend to be lipid-soluble and concentrate in the marrow
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Old 08-20-2011
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I think its A
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Old 08-20-2011
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bone marrow, GI, and skin cells are constantly dividing which is y they will get affected the most by drugs that are anti-growth drugs.

Last edited by ujustgotdoctored; 08-20-2011 at 09:14 AM.
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Old 08-20-2011
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A) Cells in the marrow divide rapidly

the target of chemo is tumor cells that divide rapidly
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Old 08-20-2011
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(A) Cells in the marrow divide rapidly
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