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  #1  
Old 08-22-2011
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Default pain in pelvis and lower back

A 62-year-old male presents to your office, complaining of generalized bone pain. When questioned further, he describes the pain is worse in his pelvis and lower back. X-rays are taken and shown in the figure. He states he has been having frequent headaches and recent hearing loss. Laboratory work shows an increase in serum alkaline phosphatase, with normal phosphorus and calcium. Which of the following neoplasms is he at risk for?
A. Osteoid osteoma
B. Osteoblastoma
C. Chondrosarcoma
D. Secondary osteosarcoma
E. Osteochondroma
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Old 08-22-2011
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its pagets ds. risk for sec. osteosarcoma,,
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  #3  
Old 08-22-2011
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D. Secondary osteosarcoma -Paget leads to osteosarcoma <1% with bad prognosis..
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Old 08-23-2011
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Default C.

Quote:
Originally Posted by ricko335 View Post
A 62-year-old male presents to your office, complaining of generalized bone pain. When questioned further, he describes the pain is worse in his pelvis and lower back. X-rays are taken and shown in the figure. He states he has been having frequent headaches and recent hearing loss. Laboratory work shows an increase in serum alkaline phosphatase, with normal phosphorus and calcium. Which of the following neoplasms is he at risk for?
A. Osteoid osteoma
B. Osteoblastoma
C. Chondrosarcoma
D. Secondary osteosarcoma
E. Osteochondroma
C. Chondrosarcoma
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  #5  
Old 08-23-2011
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Correct Answer

Quote:
Originally Posted by ricko335 View Post
A 62-year-old male presents to your office, complaining of generalized bone pain. When questioned further, he describes the pain is worse in his pelvis and lower back. X-rays are taken and shown in the figure. He states he has been having frequent headaches and recent hearing loss. Laboratory work shows an increase in serum alkaline phosphatase, with normal phosphorus and calcium. Which of the following neoplasms is he at risk for?
A. Osteoid osteoma
B. Osteoblastoma
C. Chondrosarcoma
D. Secondary osteosarcoma
E. Osteochondroma
D? mosaic pattern!!! also normal ca and p and inc ALP means paget!
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  #6  
Old 08-23-2011
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it is D...............
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Old 08-23-2011
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secondary osteosarcoma
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Old 08-23-2011
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Secondary osteosarcoma
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Old 08-24-2011
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The correct answer is D.
The X-rays show dense and disordered bone, consistent with Pagetís disease. The symptoms and laboratory values are consistent with a diagnosis of Pagetís disease. Patients with Pagetís disease are at risk for secondary osteosarcoma and fibrosarcoma. Osteochondroma, osteoid osteoma and osteoblastoma are benign bone tumors.
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