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Old 08-23-2011
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Help pulmonary circulation

can some1 explain me the graphs on page 505 of 2010 FA.this is under pulmonary circulation .these are graphs of Pao2 vs length along capillary in perfusion limited and diffusion limited situations.pls help me ...cant understand
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Old 08-23-2011
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Originally Posted by winner21 View Post
can some1 explain me the graphs on page 505 of 2010 FA.this is under pulmonary circulation .these are graphs of Pao2 vs length along capillary in perfusion limited and diffusion limited situations.pls help me ...cant understand




In first graph, start is the venous end and End is arterial end. So pO2 increases along capillary length. Deep in the exercise curve is due to increased O2 extraction.

O2,CO2 and N2O always perfusion limited and CO always diffusion limited.Plus, O2 diffusion limited in Emphysema and Fibrosis.

Second graph shows diffusion limited CO, Upper horizontal line suggests PA and even with that high concentration, it don't equilibrate with the blood means Pa=lower line. Same happens for O2 in Emphysema as decreased alveolar area(A) and in Fibrosis due to increase Thickness(T). V=A/T*D(P1-P2)

Third graph showing the early equilibration of Pa and PA. It is impaired in Pulmonary embolism. So in PE Pa will not touch the upper PA line.

Hope that helps..
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