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Old 12-26-2014
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Default help in a lil point

pt with pyloric stenosis has prolonged vomiting. most like;y biochemical change ll be ?
hypokalemia
hypovolemia
hyponatremia
high serum bicarb

key says hyponatremia...how? please make me understand
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  #2  
Old 12-26-2014
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Quote:
Originally Posted by buttercup786 View Post
pt with pyloric stenosis has prolonged vomiting. most like;y biochemical change ll be ?
hypokalemia
hypovolemia
hyponatremia
high serum bicarb

key says hyponatremia...how? please make me understand
Pyloric stenosis--> Prolonged Vomiting-->Losing mostly stomach acid-->Means losing H+=>Low serum [H+]--> Metabolic Alkalosis...
Kidneys compensate Metabolic Alkalosis by retaining H+ and secreting Na+ and HC03- in distal tubule.
Normally, Kidney absorb Na+ in distal tubule and for every Na+ absorbed, secrete K+ and H+. As body is low in H+ in prolonged vomiting...Kidney tries to preserve H+ by not absorbing Na+ and in the process we also lose HC03- to counter act alkalosis.
Ultimately, we save H+, lose Na+ leading to HypoNatremia and also lose HC03- to compensate metabolic Alkalosis.

Just read renal absorption of Na+ in distal tubule and you will understand everything, also read acid base balance.

Thanks,
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buttercup786 (12-26-2014)
  #3  
Old 12-26-2014
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thankssssssssssssss !!!!!!!!! i have another question too !

2 year old child with fever n, pallor & bowl disturbance.hb=5.6, MCV=107,MCH=340,MCHC=36... what investigation confirm diagnosis
A.intrinsic factor antibodies
B.serum vit b12

thanks for replyin
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