Why does glucagon increase insulin secretion? - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 08-26-2011
USMLE Forums Guru
 
Steps History: ---
Posts: 332
Threads: 48
Thanked 168 Times in 107 Posts
Pancreas Why does glucagon increase insulin secretion?

Kaplan Step 1 Lecture Notes says glucagon increase insulin secretion, this seems counterintuitive. Can anyone share your thoughts?
Reply With Quote Quick reply to this message
The above post was thanked by:
dr.tasneem (08-31-2011)



  #2  
Old 08-26-2011
USMLE Forums Scout
 
Steps History: Not yet
Posts: 43
Threads: 6
Thanked 26 Times in 15 Posts
Reputation: 36
Default

Well, the best way to answer a question is to get you to think it through yourself...

What is the point of gluconeogensis and glycogenolysis? It's to raise the fuel source for the body. How is the fuel (glucose) then put into the cells?
Reply With Quote Quick reply to this message
The above post was thanked by:
drgabroomunda (09-01-2011), fawazfaris (08-30-2011), menatallah Elgohary (08-30-2011), usluipek (08-26-2011)
  #3  
Old 08-26-2011
USMLE Forums Addict
 
Steps History: Not yet
Posts: 96
Threads: 5
Thanked 68 Times in 36 Posts
Reputation: 78
Default

because insulin is needed for glucose transport if I recall correctly.
Reply With Quote Quick reply to this message
The above post was thanked by:
usluipek (08-26-2011)
  #4  
Old 08-30-2011
USMLE Forums Master
 
Steps History: Step 1 Only
Posts: 566
Threads: 25
Thanked 522 Times in 263 Posts
Reputation: 532
Default

You guys are right.

Glucagon increase liver Glucogenolysis, ketogenesis, ureagenesis, lypolisys. In order to do that it needs to get into the liver, for the glucagon to do that it needs insulin to get into the liver, this is why glucagon needs to increase Insulin secretion.
Reply With Quote Quick reply to this message
The above post was thanked by:
menatallah Elgohary (08-30-2011), ricko335 (08-30-2011), usluipek (08-30-2011), zohra (09-02-2011)
  #5  
Old 08-30-2011
USMLE Forums Scout
 
Steps History: 1 + CS
Posts: 90
Threads: 23
Thanked 14 Times in 9 Posts
Reputation: 24
Default

Hi guys....putting it in a much simpler way; During hypoglycemia glucagon is stimulated ----> glucagon makes sugar ----> sugar is in the blood BUT As we all know sugar by it self wont be taken up by the cell ----> Insulin then is called in to push it into the cell....

Note: The ONLY special case were insulin is not required to push in the sugar is the actively working muscle. correct me if am mistaken...

Good luck to all....
Reply With Quote Quick reply to this message
The above post was thanked by:
aknz (08-31-2011), Shimche0244 (08-30-2011), usluipek (09-01-2011), zohra (09-02-2011)
  #6  
Old 08-30-2011
USMLE Forums Scout
 
Steps History: Not yet
Posts: 14
Threads: 5
Thanked 7 Times in 3 Posts
Reputation: 17
Default Reg the counter regulatory action of Glucagon for Insulin

The ff are the counter regulatory hormones....
Glucagon
Cortisol
Growth hormone
Epinephrine

These hormone levels will be high if the Insulin level is low....
The reason is quite simple ....becoz to maintain the blood glucose level in homeostatis ...... if they are nt opposite in action, then ppl would always remain in hypoglycemic world!!
Reply With Quote Quick reply to this message
  #7  
Old 08-31-2011
dr.tasneem's Avatar
USMLE Forums Scout
 
Steps History: Not yet
Posts: 29
Threads: 0
Thanked 7 Times in 6 Posts
Reputation: 17
Post glucagon

glucagon enhance hepatic glycogenolysis and gluconeogenesis ....both of these mechanisms will increase blood glucose level .........this increase will lead to increase secretion of insulin ......
Reply With Quote Quick reply to this message
The above post was thanked by:
usluipek (09-01-2011)
  #8  
Old 09-01-2011
USMLE Forums Scout
 
Steps History: Not yet
Posts: 70
Threads: 5
Thanked 13 Times in 10 Posts
Reputation: 23
Default

Quote:
Originally Posted by usluipek View Post
Kaplan Step 1 Lecture Notes says glucagon increase insulin secretion, this seems counterintuitive. Can anyone share your thoughts?

Hey...folks...
Choose that glucagon raises insuline ...and you guys will get CERO points for that.
The explanations u give are not valid. Those are justifications for the missense of kaplan.

The increase in insuline is because the raising in glucose. ...but glucose can be raisen by many things.
Be careful.
Reply With Quote Quick reply to this message
The above post was thanked by:
phantom86 (09-01-2011)
  #9  
Old 09-01-2011
USMLE Forums Scout
 
Steps History: 1 + CS
Posts: 90
Threads: 23
Thanked 14 Times in 9 Posts
Reputation: 24
Default

Totaly agree with chemole.....glucagon has nothing to do with stimulating insulin by it self. Its all about the sugar, they are two totaly opposite to each other. By comon sense how come glucagon stimulates its counter hormone, if so then non will be produced as they will eliminate each other at the moment they are released.....Sugar Babe;everybody runs after her, take it like that?!?!!?
Reply With Quote Quick reply to this message



Reply

Tags
Endocrine-, Physiology-

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
how hydroxyurea increase Hbf synthesis? yasirsattar75 USMLE Step 1 Forum 1 07-18-2011 08:03 PM
Glucagon content question jahn77 USMLE Step 1 Forum 3 07-12-2011 07:25 AM
Glucagon vs Glucose vs Gluconeogenesis vs Glycolsis bigal USMLE Step 1 Forum 8 07-10-2011 11:53 PM
how to increase uworld score? medicine USMLE Step 2 CK Forum 1 03-11-2011 01:20 AM
Prostatic secretion vs Seminal Vesicle secretion lemontea88 USMLE Step 1 Forum 1 12-07-2009 02:44 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)