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  #1  
Old 08-29-2011
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ObGyn Vaginal spotting in a postmenopausal woman

A 75-year-old woman presents to the physician with a chief complaint of vaginal spotting. She has been postmenopausal for 25 years and does not take hormones. An ultrasound shows a mass in the uterine fundus. A hysterectomy is performed, and pathologic examination of the removed uterus reveals a malignant tumor of the endometrial glands and stroma. Which of the following is the most likely diagnosis?

(A) Endolymphatic stromal myosis
(B) Endometrial carcinoma
(C) Endometrial stromal sarcoma
(D) Leiomyosarcoma
(E) Malignant mixed mullerian tumor
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Old 08-29-2011
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B. leiomyosarcome
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Old 08-29-2011
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endometrial CA
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Old 08-29-2011
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B. ENDOMETRIAL CARCINOMA

(not leiomyosarcoma)
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Endometrial CA. is not the right answer....
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Old 08-29-2011
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i think its c ...sureeeeee coz its seems to b something like endometriosis and endometrial stroma cancer with glandds is the right option so its c 95 percent sure
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Old 08-29-2011
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I think C as well............
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Old 08-29-2011
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it's E i guess because it's a mix of stroma and endometrium (epith)
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Quote:
Originally Posted by bebix View Post
Endometrial CA. is not the right answer....
I think most common cause for post menopausal bleed is Endometrial Ca.
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E. Is a Carcinosarcoma, also called mullerian mixed malignant tumor
It has epithelial (endometrial glands) and mesenchymal (sarcomatous) elements.
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Old 08-29-2011
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The answer is E, is common among older pte postmenopause and is common to bleed. It conaints both tissue, stromal and Epithelial as the name suggest, "Mixed"...

B, cant be because usually pte is expose to estrogen which this pte doesnt give any clue of that. There is no stromal component of this tumor.

C/D are not correct because they do have Stromal ( Right ) but they dont have Epithelial component...
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Quote:
Originally Posted by rulz View Post
The answer is E, is common among older pte postmenopause and is common to bleed. It conaints both tissue, stromal and Epithelial as the name suggest, "Mixed"...

B, cant be because usually pte is expose to estrogen which this pte doesnt give any clue of that. There is no stromal component of this tumor.

C/D are not correct because they do have Stromal ( Right ) but they dont have Epithelial component...
Yup, the correct answer is E) Malignant mixed mullerian tumor (malignant tumor of the endometrial glands and stroma)
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