Pheochromocytoma, Thyroid Diseas, and Oncogenesis! - USMLE Forums
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Old 09-05-2011
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Thyroid Pheochromocytoma, Thyroid Diseas, and Oncogenesis!

A 38-year-old male presents to the emergency room complaining of diarrhea and a neck mass. He also states he has been extremely tired the past several weeks. On examination, his blood pressure is 210/120. An abdominal CAT scan is performed, showing a pheochromocytoma. Ultrasound is also performed of the neck, showing a mass in the thyroid. Lab work shows hypercalcemia and hyperparathyroidism. Which of the following oncogenes is associated with this condition?

A. C-kit
B. Ret
C. Erb-B2
D. Abl
E. Ras
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Old 09-05-2011
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B. Ret

Men 2A 2B associated with Ret gene.
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Old 09-05-2011
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ret...............
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Old 09-05-2011
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B. Ret

MEN 2B
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Old 09-05-2011
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Ret / Gain function / Proto-Oncogen.
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