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  #1  
Old 09-09-2011
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Question Muscle Fatigue and a Chest X Ray!

A 73-year-old male presents to your office complaining of muscle fatigue. He also complains of a dry mouth and impotence. A routine chest x-ray is done and shown in the figure. Laboratory work shows normal calcium levels. What is the etiology of his symptoms?
A. Antibodies to sodium channels
B. Antibodies to calcium channels
C. Antibodies to antidiuretic hormone
D. Antibodies to acetylcholine
E. Antibodies to potassium channels

Muscle Fatigue and a Chest X Ray!-cxr_rll_mass.jpg
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Old 09-09-2011
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Default ????????????

i want to eliminate, i have no idea of the answer

he has a lung pathology, was thinking of lung CA so he might have SIADH BUT he shouldn't have dry mouth with that.

he could have sarcoid (unlikely) and is overproducing vitamin D, there is a link between hypercalcemia and excess urine (i think, not sure) leading to dry mouth. but there is normal calcium. so thats out!

antibody to ADH should produce diuresis that can cause dry mouth.

antibody to Ach can cause dry mouth and impotence, i will go with antibody to ACh

Last edited by nativedoc2; 09-09-2011 at 04:31 PM.
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Old 09-09-2011
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E. Antibodies to potassium channels .... just a guess.
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Old 09-09-2011
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C.Antibody to adh
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Old 09-09-2011
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D. Antibodies to acetylcholine
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  #6  
Old 09-09-2011
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Antibodies to Ach (muscle weakness, dry mouth and impotence),but what about lung mass??
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Old 09-09-2011
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b. lambert eaton syndrome - small cell lunger cancer?
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Old 09-09-2011
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Quote:
Originally Posted by jattdoc View Post
b. lambert eaton syndrome - small cell lunger cancer?


I go with Lambert-Eaton,
B)
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Old 09-10-2011
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dry mouth-acetycholine? D?

could it be sjogren?
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Old 09-10-2011
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b??

wats the right answer?
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Old 09-10-2011
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its B i think so it seems to b L.E syndrome
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I think is B, with a paraneoplastic syndrome (L.E Syndrome)
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lambert eaton syndrome .... antibodies to presynaptic ca channel , have autonomic symptoms and association with lung carcinoma
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Old 09-10-2011
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Lambert–Eaton myasthenic syndrome --> B. Antibodies to calcium channels
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Old 09-10-2011
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its D, i guess
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Old 09-11-2011
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It is lambort eaton syndrome antibodies to calcium channels
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