Life long history of chronic lung infections! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 09-12-2011
USMLE Forums Addict
 
Steps History: ---
Posts: 191
Threads: 69
Thanked 149 Times in 75 Posts
Reputation: 159
Immunology Life long history of chronic lung infections!

An 18-year-old man is evaluated for possible immunodeficiency disease because of a lifelong history of chronic lung infections, recurrent otitis media, and multiple episodes of bacterial meningitis. Serum immunoglobulin levels are as follows: IgM 300 mg/dL, IgG 660 mg/dL, IgA 10 mg/dL. Which of the following additional signs is this patient most likely to exhibit?
a. contact dematitis
b. decreased phagocyte efficiency
c. immune complex disease
d. increased atopy
e. partial albinism
Reply With Quote Quick reply to this message
The above post was thanked by:
aknz (09-13-2011), usmle2011 (09-13-2011)



  #2  
Old 09-12-2011
akua's Avatar
USMLE Forums Addict
 
Steps History: Not yet
Posts: 167
Threads: 0
Thanked 31 Times in 31 Posts
Reputation: 41
Default

A.contact dermatitis
Reply With Quote Quick reply to this message
  #3  
Old 09-12-2011
laurier's Avatar
USMLE Forums Addict
 
Steps History: CK Only
Posts: 105
Threads: 19
Thanked 69 Times in 32 Posts
Reputation: 79
Default

IgA are low.
I would choose DD. increased atopy.
Reply With Quote Quick reply to this message
The above post was thanked by:
menatallah Elgohary (09-13-2011)
  #4  
Old 09-13-2011
jaimin's Avatar
USMLE Forums Veteran
 
Steps History: 1+CK+CS+3
Posts: 264
Threads: 15
Thanked 98 Times in 56 Posts
Reputation: 108
Default

Quote:
Originally Posted by laurier View Post
IgA are low.
I would choose DD. increased atopy.
What is relation between Atopy and IgA ????
Atopy is type 1 HS. Thats IgE related.
Reply With Quote Quick reply to this message
  #5  
Old 09-13-2011
USMLE Forums Addict
 
Steps History: ---
Posts: 191
Threads: 69
Thanked 149 Times in 75 Posts
Reputation: 159
Correct Answer The correct answer is > D increase atopy

the serum level values in this case are all normal execpt for IgA which is low , patients of selective IgA deficiency which have an increased amount of atopic allergy it seems that because their inability to produce IgA they isotype to IgE more frequently

it can,t be contact dermatitis as it is a type od DTH ( delayed type hypersenstivity) depending on T helper cells , macrophages and cytotoxic lymphocytes and not increase in IgA deficiences

immune complex disease > it not corrected as it is realted with complement difiecncies

partial albinism >> have nothing to do with such case as it related to chediak higashi syndrome
Reply With Quote Quick reply to this message
The above post was thanked by:
aknz (09-14-2011), donofitaly (09-13-2011), jaimin (09-13-2011)
  #6  
Old 09-13-2011
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 623
Threads: 111
Thanked 424 Times in 264 Posts
Reputation: 434
Default

Quote:
Originally Posted by menatallah Elgohary View Post
An 18-year-old man is evaluated for possible immunodeficiency disease because of a lifelong history of chronic lung infections, recurrent otitis media, and multiple episodes of bacterial meningitis. Serum immunoglobulin levels are as follows: IgM 300 mg/dL, IgG 660 mg/dL, IgA 10 mg/dL. Which of the following additional signs is this patient most likely to exhibit?
a. contact dematitis
b. decreased phagocyte efficiency
c. immune complex disease
d. increased atopy
e. partial albinism
d. increased atopy??
Reply With Quote Quick reply to this message
The above post was thanked by:
menatallah Elgohary (09-13-2011)
  #7  
Old 09-13-2011
USMLE Forums Master
 
Steps History: Not yet
Posts: 674
Threads: 264
Thanked 959 Times in 393 Posts
Reputation: 969
Send a message via Yahoo to ricko335
Default

increased atopy
Reply With Quote Quick reply to this message
The above post was thanked by:
menatallah Elgohary (09-13-2011)



Reply

Tags
Immunology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Arterial PO2 decreases with chronic lung disease because physiologic shunt decreases O2 extraction ratio DoctorB USMLE Step 1 Forum 3 03-27-2011 01:27 PM
The life cycle of this parasite? kemoo USMLE Step 1 Forum 3 01-06-2011 11:46 AM
Residencies Life?? silakan_isi IMG Residency Match Forum 3 10-24-2010 04:08 PM
Residencies Life? silakan_isi IMG Residency Match Forum 0 06-23-2010 06:24 AM
Research Drug Half Life? Yallah USMLE Step 1 Forum 3 04-19-2010 07:43 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)