Transfected mice Immunity question - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 02-15-2010
USMLE Forums Scout
 
Steps History: Not yet
Posts: 33
Threads: 30
Thanked 55 Times in 22 Posts
Reputation: 65
Immunology Transfected mice Immunity question

In the lab you have two groups of mice. You transfected group 1 with a gene that makes them produce more IL2. The other group 2 you did not transfect. Then you inoculated both groups with tumor cells. You noticed an enhanced immunity in group 1. This enhanced immunity can be explained by proliferation of which of the following cell type?

A- Neutrophils
B- Macrophages
C- T lymphocytes
D- Dendritic cells
E- Mast cells
Reply With Quote Quick reply to this message
The above post was thanked by:
aktorque (02-22-2011), Dulbee (02-22-2011), Mondoshawan (02-22-2011), swati (02-22-2011), wahaha007 (02-16-2010)



  #2  
Old 02-15-2010
ashishkabir's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 625
Threads: 19
Thanked 374 Times in 221 Posts
Reputation: 394
Default

My vote is for C since IL-2 receptors are on lymphocytes.. What do you guys think?
Reply With Quote Quick reply to this message
The above post was thanked by:
wahaha007 (02-16-2010)
  #3  
Old 02-15-2010
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 742
Threads: 137
Thanked 2,446 Times in 441 Posts
Reputation: 2549
Default

Yes I agree with you, the correct answer is T lymphocytes
Reply With Quote Quick reply to this message
The above post was thanked by:
wahaha007 (02-16-2010)
 
  #4  
Old 02-22-2011
USMLE Forums Scout
 
Steps History: Step 1 Only
Posts: 61
Threads: 3
Thanked 76 Times in 29 Posts
Reputation: 86
Default

Nice question
Reply With Quote Quick reply to this message
  #5  
Old 02-22-2011
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 335
Threads: 24
Thanked 295 Times in 152 Posts
Reputation: 305
Default

T lymphocytes! IL2 is a TH1 promoter. And immunity against tumors is cytotoxic.
Reply With Quote Quick reply to this message
  #6  
Old 02-22-2011
USMLE Forums Guru
 
Steps History: Step 1 Only
Posts: 487
Threads: 95
Thanked 1,459 Times in 357 Posts
Reputation: 1469
Arrow C) T lymphocytes

The correct ans is C) T lymphocytes

Its a straight forward qn. Let me show you the entire immunological t-cell activation and proliferation pathway.

Transfected mice Immunity question-tcell_2.gif
click image to enlarge

Transfected mice Immunity question-t_cell_activation.png
click image to enlarge
Reply With Quote Quick reply to this message



Reply

Tags
Figures-, Immunology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
question help: diabetic foot related question dezirablize USMLE Step 2 CK Forum 5 01-15-2015 02:42 PM
Video Animation to understand Immunity! Dulbee USMLE Step 1 Forum 1 05-01-2011 12:10 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)