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  #1  
Old 10-01-2011
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Blood 72-Yr-Old Man with Leukocytosis and this blood film!

A 72-year-old man presents with increasing fatigue. Physical examination reveals an elderly man in no apparent distress (NAD). He is found to have multiple enlarged, nontender lymph nodes along with an enlarged liver and spleen. Laboratory examination of his peripheral blood reveals a normocytic normochromic anemia, a slightly decreased platelet count, and a leukocyte count of 72,000 cells/L. An example of his peripheral blood is seen in the picture below. Which of the following is the most likely diagnosis?

72-Yr-Old Man with Leukocytosis and this blood film!-blood.jpg
click image to enlarge

A. Acute lymphoblastic leukemia
B. Atypical lymphocytosis
C. Chronic lymphocytic leukemia
D. Immunoblastic lymphoma
E. Prolymphocytic leukemia
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  #2  
Old 10-01-2011
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C.
Chronic lymphocytic leukemia
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  #3  
Old 10-01-2011
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i m with c ....
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  #4  
Old 10-01-2011
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Correct Answer

CLL
Age fits
It's normally asmptomatic except for LN enlargement
Has presence of lyphocytes and smudge cells in blood picture
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  #5  
Old 10-01-2011
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CLL is the answer
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  #6  
Old 10-01-2011
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Correct Answer Answer

CLL is correct.
SOME CLUES:
1) Age>60
2) often asymptomatic but when it is symptomatic you note
-----------Lymphadenopathy
-----------Hepatosplenomgaly
-----------WBC count 50,000 - 200,000
-----------Smudge cells in blood smear
-----------CD19+, CD20+, CD5+ BUT CD10- B-lymphocytes in blood smear

72-Yr-Old Man with Leukocytosis and this blood film!-chronic_lymphocytic_leukemia.jpg
click image to enlarge
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  #7  
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i agree with c
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  #8  
Old 10-04-2011
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Default

[QUOTE=m82_ghasemi;71002]CLL is correct.
SOME CLUES:
1) Age>60
2) often asymptomatic but when it is symptomatic you note
-----------Lymphadenopathy
-----------Hepatosplenomgaly
-----------WBC count 50,000 - 200,000
-----------Smudge cells in blood smear
-----------CD19+, CD20+, CD5+ BUT CD10- B-lymphocytes in blood smear

it is c
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Blood-Films, Hematology-, Pathology-, Step-1-Questions

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